日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Host-derived nitrate fuels indole production by Escherichia coli to drive chronic kidney disease progression

宿主来源的硝酸盐促进大肠杆菌产生吲哚,从而加速慢性肾病进展。

Lee, Jee-Yon; Mahan, Scott P; Parente de Carvalho, Thaynara; Nguyen, Henry; Singai, Chonikarn; Camacho, Lizbeth; Tekeli, Mert; Kwon, Yu-Jin; Lee, Ji-Won; Santos, Renato L; Tsolis, Renée M; Winter, Sebastian E; Bäumler, Andreas J

Paraspeckle condensation is controlled via TDP-43 polymerization and linked to neuroprotection.

核旁斑的凝聚是通过 TDP-43 聚合控制的,并且与神经保护有关。

Hodgson Rachel E, Huang Wan-Ping, Lang Ruaridh, Kumar Vedanth, An Haiyan, Stender Emil G P, Chalakova Zhaklin P, Driver Mark D, Sanchez Avila Anna, Ellis Brittany C S, Day Emily, Rayment Jessica A, Baeg Kyungmin, Strange Andrew, Moll Tobias, Wright Gareth S A, van Vugt Joke J F A, Allen Scott P, Locker Nicolas, Pitout Ianthe, Fletcher Susan, Onck Patrick R, Duss Olivier, Cooper-Knock Johnathan, Shelkovnikova Tatyana A

Cytoplasmic NAD/H synthesis via NRK1 regulates inflammatory capacity and promotes survival of CD4(+) T cells

胞质NAD/H合成通过NRK1调节炎症能力并促进CD4(+) T细胞的存活。

Stavrou, Victoria; Ali, Myah; Gudgeon, Nancy; Bishop, Emma L; Fulton-Ward, Taylor; Turley, Bethany; Heising, Silke; Mohamed, Sally H; Hain, Sofia; George, Lorna; Deng, Minghao; McCowan, Jack; Sheriff, Lozan; Davies, Scott P; Marzullo, Bryan; Tennant, Daniel A; Doig, Craig L; Bending, David A; Roberts, Ed W; Lavery, Gareth G; Drummond, Rebecca A; Dimeloe, Sarah

CD38 expression by neonatal human naive CD4+ T cells shapes their distinct metabolic and tolerogenic properties.

新生儿幼稚 CD4+ T 细胞表达 CD38,从而塑造其独特的代谢和耐受特性。

Dwyer Laura R, DeRogatis Andrea M, Clancy Sean, Gouirand Victoire, Chien Charles, Rogers Elizabeth E, Oltman Scott P, Jelliffe-Pawlowski Laura L, van den Broek Theo, van Wijk Femke, Lynch Susan V, Rutishauser Rachel L, Wagner Allon, Combes Alexis J, Scharschmidt Tiffany C

Acute neuronal inhibition response caused by phosphorothioate antisense oligonucleotides following local delivery to the central nervous system

局部递送硫代磷酸酯反义寡核苷酸至中枢神经系统后引起的急性神经元抑制反应

O'Rourke, Jacqueline G; Bachmann, Gemma; Mazur, Curt; Zhou, Keming; Platoshyn, Oleksandr; Bravo Hernandez, Mariana; Klein, Stephanie K; Nguyen, Jonathon; Burel, Sebastien; Hoffmaster, Christine; Zanardi, Thomas; Jafar-Nejad, Paymaan; Marsala, Martin; Henry, Scott P; Swayze, Eric E; Powers, Berit; Kordasiewicz, Holly B

Alpha-gal-specific human IgE promotes both alpha-gal-induced and antigen-independent allergic effector cell activation

α-半乳糖特异性人IgE可促进α-半乳糖诱导的和抗原非依赖性的过敏效应细胞活化。

Wang, Yinghui; Zhang, Yugen; Dudley, Christa; Fitzgerald, Katherine; Carson, Audrey S; Kapita, Camille M; Rana, Daaniya; Kluckman, Kim; Bortner, Donna; Cowley, Dale O; Travis, Christopher R; Vorobiov, Julia; Choudhary, Shailesh; Kepley, Christopher L; Commins, Scott P; Smith, Scott A; Iweala, Onyinye I

Circulating exhausted CD8+ effector memory cells differentiate immune checkpoint inhibitor-induced liver injury from other acute immune-mediated liver injuries

循环中耗竭的CD8+效应记忆细胞可将免疫检查点抑制剂引起的肝损伤与其他急性免疫介导的肝损伤区分开来。

Astbury, Stuart; Atallah, Edmond; Grove, Jane I; Bozward, Amber G; Davies, Scott P; Sheehan, Mark J; Kumpf, Steven W; Qian, Jessie; Krajewska, Natalia M; Wootton, Grace E; Lingaya, Melanie R; Kresnik, Davor; Radulescu, Flavia; Rao, Ankit; Franks, Hester; Ruiz-Ortega, Lourdes; Riveiro-Barciela, Mar; Ramaiah, Shashi K; Lanz, Thomas A; Ji, Changhua; Patel, Poulam M; Oo, Ye H; Aithal, Guruprasad P

Hypothesis-free evaluation of circulating metabolome provides cell-specific insights regarding the role of energy substrate availability in amyotrophic lateral sclerosis

对循环代谢组进行无假设评估,可提供关于能量底物可用性在肌萎缩侧索硬化症中作用的细胞特异性见解

Alhathli, Elham; Cooper-Knock, Johnathan; Girach, Zain-Ul-Abideen; Julian, Thomas H; Bauer, Claudia; Timmons, Hannah O; Ward, Billie D; Walker, Heather; Azzouz, Mimoun; Elrayess, Mohamed A; Al-Khelaifi, Fatima; Yousri, Noha A; Gul, Aytac; Kelsall, Alan; Moll, Tobias; Harvey, Calum; Gornall, Sarah; Wong, Kari; Allen, Scott P; Strange, Andrew; Shaw, Pamela J

Impaired hepatic metabolism in Hereditary Fructose Intolerance confers fructose-independent risk for steatosis and hypertriglyceridemia.

遗传性果糖不耐受症患者的肝脏代谢受损,导致与果糖无关的脂肪变性和高甘油三酯血症风险。

Fulham Melissa A, Griffin John D, Perez Sylvie, Sun Zhongyuan, Daurio Natalie A, Xing Gang, Clasquin Michelle F, Miller Melissa R, Hyde Craig L, Kelly Scott P, Boucher Magalie, Poskanzer Rachel, Gamini Ramya, Pashos Evanthia, Zhang Ying, Kuang Elaine, Fienman Josh, Bence Kendra K, Tesz Gregory J

Biomechanical Analysis of the Effects of Knee Savers on Knee Joint Loading During High Knee-Flexion Tasks

膝关节保护器对高膝关节屈曲动作中膝关节负荷影响的生物力学分析

Zheng, Liying; Wu, John Z; Moore, Kevin D; Hawke, Ashley L; Carey, Robert E; Warren, Christopher M; Breloff, Scott P