Scott-Browne相关文献与解析，生知库 | 链接生命科学的每一步

DeGolier, Kole R; Pham-Danis, Catherine; Burciaga, Samuel D; Walsh, Zachary H; Brzezinski, Christine; Novak, Amanda J; Leach, Lillie; Cimons, Jennifer; Li, Wei; Zhongyu, Zhu; Dimitrov, Dimiter; Scott-Browne, James P; Kohler, M Eric; Fry, Terry J

CD22

CD2

发表日期：2026

文献求助收藏

Antigen experience history directs distinct functional states of CD8+ CAR T cells during the antileukemia response

抗原经历史决定了CD8+ CAR T细胞在抗白血病反应期间的不同功能状态

期刊:Nature Immunology

影响因子:27.7

doi:10.1038/s41590-024-02034-1

Kole R DeGolier ，Etienne Danis ，Marc D'Antonio ，Jennifer Cimons ，Michael Yarnell ，Ross M Kedl ，M Eric Kohler ，James P Scott-Browne ，Terry J Fry

Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch

Tet基因的诱导性破坏会导致髓系恶性肿瘤、转录延伸以及异染色质向常染色质的转换。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2214824120

Yuita, Hiroshi; López-Moyado, Isaac F; Jeong, Hyeongmin; Cheng, Arthur Xiuyuan; Scott-Browne, James; An, Jungeun; Nakayama, Toshinori; Onodera, Atsushi; Ko, Myunggon; Rao, Anjana

A bifurcated role for c-Maf in Th2 and Tfh2 cells during helminth infection.

c-Maf 在蠕虫感染期间对 Th2 和 Tfh2 细胞发挥双重作用

期刊:Mucosal Immunology

影响因子:7.6

doi:10.1016/j.mucimm.2023.04.002

Bao Katherine, Isik Can Uryan, Miller Mindy M, Brown Ivy K, Dell'Aringa Mark, Dooms Hans, Seibold Max A, Scott-Browne James, Lee Reinhardt Richard

细胞生物学

发表日期：2023

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Antigen experience history directs distinct functional states of CD8+ CAR T cells during the anti-leukemia response

抗原经历史指导抗白血病反应期间 CD8+ CAR T 细胞的不同功能状态

期刊:

影响因子:

doi:10.21203/rs.3.rs-3712137/v1

Kole R DeGolier, Etienne Danis, Marc D'Antonio, Jennifer Cimons, Michael Yarnell, Ross M Kedl, M Eric Kohler, James P Scott-Browne, Terry J Fry

肿瘤

白血病

T细胞

Functional/Block/Neutralize

Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure

iNKT 细胞的转录组和染色质景观受亚群分化和抗原暴露的影响

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-021-21574-w

Mallory Paynich Murray #, Isaac Engel #, Grégory Seumois #, Sara Herrera-De la Mata, Sandy Lucette Rosales, Ashu Sethi, Ashmitaa Logandha Ramamoorthy Premlal, Goo-Young Seo, Jason Greenbaum, Pandurangan Vijayanand, James P Scott-Browne, Mitchell Kronenberg

Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells

缺氧诱导因子活性促进 CD8+ T 细胞的抗肿瘤效应功能和组织驻留

期刊:Journal of Clinical Investigation

影响因子:13.3

doi:10.1172/JCI143729

Ilkka Liikanen, Colette Lauhan, Sara Quon, Kyla Omilusik, Anthony T Phan, Laura Barceló Bartrolí, Amir Ferry, John Goulding, Joyce Chen, James P Scott-Browne, Jason T Yustein, Nicole E Scharping, Deborah A Witherden, Ananda W Goldrath

肿瘤

T细胞

Functional/Block/Neutralize

Single cell analysis of host response to helminth infection reveals the clonal breadth, heterogeneity, and tissue-specific programming of the responding CD4+ T cell repertoire

宿主对蠕虫感染反应的单细胞分析揭示了响应 CD4+ T 细胞库的克隆广度、异质性和组织特异性编程

期刊:PLoS Pathogens

影响因子:5.5

doi:10.1371/journal.ppat.1009602

Ivy K Brown, Nathan Dyjack, Mindy M Miller, Harsha Krovi, Cydney Rios, Rachel Woolaver, Laura Harmacek, Ting-Hui Tu, Brian P O'Connor, Thomas Danhorn, Brian Vestal, Laurent Gapin, Clemencia Pinilla, Max A Seibold, James Scott-Browne, Radleigh G Santos, R Lee Reinhardt

An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia

体内全基因组 CRISPR 筛选确定 RNA 结合蛋白 Staufen2 是髓系白血病的关键调节因子

期刊:Nature Cancer

影响因子:23.5

doi:10.1038/s43018-020-0054-2

Jeevisha Bajaj, Michael Hamilton #, Yutaka Shima #, Kendall Chambers, Kyle Spinler, Eric L Van Nostrand, Brian A Yee, Steven M Blue, Michael Chen, David Rizzeri, Charles Chuah, Vivian G Oehler, H Elizabeth Broome, Roman Sasik, James Scott-Browne, Anjana Rao, Gene W Yeo, Tannishtha Reya2

Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells

胸腺 iNKT 单细胞分析揭示了小鼠固有 T 细胞的共同发育程序

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-020-20073-8

S Harsha Krovi ，Jingjing Zhang ，Mary Jessamine Michaels-Foster ，Tonya Brunetti ，Liyen Loh ，James Scott-Browne ，Laurent Gapin

Rational redesign of antigen binding domain improves in vivo efficacy of the CD22-CAR

对抗原结合域进行合理重新设计可提高CD22-CAR的体内疗效。

Antigen experience history directs distinct functional states of CD8+ CAR T cells during the antileukemia response

抗原经历史决定了CD8+ CAR T细胞在抗白血病反应期间的不同功能状态

Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch

Tet基因的诱导性破坏会导致髓系恶性肿瘤、转录延伸以及异染色质向常染色质的转换。

A bifurcated role for c-Maf in Th2 and Tfh2 cells during helminth infection.

c-Maf 在蠕虫感染期间对 Th2 和 Tfh2 细胞发挥双重作用

Antigen experience history directs distinct functional states of CD8+ CAR T cells during the anti-leukemia response

抗原经历史指导抗白血病反应期间 CD8+ CAR T 细胞的不同功能状态

Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure

iNKT 细胞的转录组和染色质景观受亚群分化和抗原暴露的影响

Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells

缺氧诱导因子活性促进 CD8+ T 细胞的抗肿瘤效应功能和组织驻留

Single cell analysis of host response to helminth infection reveals the clonal breadth, heterogeneity, and tissue-specific programming of the responding CD4+ T cell repertoire

宿主对蠕虫感染反应的单细胞分析揭示了响应 CD4+ T 细胞库的克隆广度、异质性和组织特异性编程

An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia

体内全基因组 CRISPR 筛选确定 RNA 结合蛋白 Staufen2 是髓系白血病的关键调节因子

Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells

胸腺 iNKT 单细胞分析揭示了小鼠固有 T 细胞的共同发育程序