Scrable相关文献与解析，生知库 | 链接生命科学的每一步

Survival of irradiated recipient mice after transplantation of bone marrow from young, old and "early aging" mice

接受辐射的受体小鼠在移植年轻、年老和“早衰”小鼠的骨髓后存活率

期刊:Aging-Us

影响因子:

doi:10.18632/aging.100867

Ian Guest, Zoran Ilic, Heidi Scrable, Stewart Sell

P44, the 'longevity-assurance' isoform of P53, regulates tau phosphorylation and is activated in an age-dependent fashion

P44 是 P53 的“长寿保证”异构体，可调节 tau 磷酸化，并以年龄依赖性方式激活

期刊:Aging Cell

影响因子:8

doi:10.1111/acel.12192

Mariana Pehar, Mi Hee Ko, Mi Li, Heidi Scrable, Luigi Puglielli

表观遗传

发表日期：2014

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p53 isoform profiling in glioblastoma and injured brain

胶质母细胞瘤和脑损伤中p53亚型谱分析

期刊:Oncogene

影响因子:7.3

doi:10.1038/onc.2012.322

Takahashi, R; Giannini, C; Sarkaria, J N; Schroeder, M; Rogers, J; Mastroeni, D; Scrable, H

Development of a Positive-readout Mouse Model of siRNA Pharmacodynamics

siRNA 药效学阳性读出小鼠模型的开发

期刊:Molecular Therapy-Nucleic Acids

影响因子:6.5

doi:10.1038/mtna.2013.63

Mark Stevenson, Robert Carlisle, Ben Davies, Chris Preece, Michelle Hammett, Wei-Li Liu, Kerry David Fisher, Amy Ryan, Heidi Scrable, Leonard William Seymour

Glucose Tolerance in Mice is Linked to the Dose of the p53 Transactivation Domain

小鼠的葡萄糖耐量与p53转录激活结构域的剂量相关

期刊:Endocrine Research

影响因子:1.8

doi:10.3109/07435800.2012.735735

Franck, Debra; Tracy, Laura; Armata, Heather L; Delaney, Christine L; Jung, Dae Young; Ko, Hwi Jin; Ong, Helena; Kim, Jason K; Scrable, Heidi; Sluss, Hayla K

发表日期：2013

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Δ40 Isoform of p53 controls β-cell proliferation and glucose homeostasis in mice

Δ40 同工型 p53 控制小鼠 β 细胞增殖和葡萄糖稳态

期刊:Diabetes

影响因子:6.2

doi:10.2337/db09-1379

Charlotte Hinault, Dan Kawamori, Chong Wee Liew, Bernhard Maier, Jiang Hu, Susanna R Keller, Raghavendra G Mirmira, Heidi Scrable, Rohit N Kulkarni

Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death

小鼠中 p53:p44 长寿保证活性改变导致记忆丧失、神经退化和过早死亡

期刊:Aging Cell

影响因子:8

doi:10.1111/j.1474-9726.2010.00547.x

Mariana Pehar, Kenneth J O'Riordan, Melissa Burns-Cusato, Matthew E Andrzejewski, Carlos Gil del Alcazar, Corinna Burger, Heidi Scrable, Luigi Puglielli

Delta40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs

Delta40p53通过调节胚胎干细胞中的IGF信号通路来控制从多能性到分化的转变。

期刊:Genes & Development

影响因子:7.7

doi:10.1101/gad.1987810

Ungewitter, Erica; Scrable, Heidi

Antagonistic pleiotropy and p53

拮抗性多效性和p53

期刊:Mechanisms of Ageing and Development

影响因子:5.1

doi:10.1016/j.mad.2008.06.002

Ungewitter, Erica; Scrable, Heidi

发表日期：2009

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Mechano growth factor, a splice variant of IGF-1, promotes neurogenesis in the aging mouse brain

机械生长因子是 IGF-1 的剪接变体，可促进衰老小鼠大脑中的神经发生

Survival of irradiated recipient mice after transplantation of bone marrow from young, old and "early aging" mice

接受辐射的受体小鼠在移植年轻、年老和“早衰”小鼠的骨髓后存活率

P44, the 'longevity-assurance' isoform of P53, regulates tau phosphorylation and is activated in an age-dependent fashion

P44 是 P53 的“长寿保证”异构体，可调节 tau 磷酸化，并以年龄依赖性方式激活

p53 isoform profiling in glioblastoma and injured brain

胶质母细胞瘤和脑损伤中p53亚型谱分析

Development of a Positive-readout Mouse Model of siRNA Pharmacodynamics

siRNA 药效学阳性读出小鼠模型的开发

Glucose Tolerance in Mice is Linked to the Dose of the p53 Transactivation Domain

小鼠的葡萄糖耐量与p53转录激活结构域的剂量相关

Δ40 Isoform of p53 controls β-cell proliferation and glucose homeostasis in mice

Δ40 同工型 p53 控制小鼠 β 细胞增殖和葡萄糖稳态

Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death

小鼠中 p53:p44 长寿保证活性改变导致记忆丧失、神经退化和过早死亡

Delta40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs

Delta40p53通过调节胚胎干细胞中的IGF信号通路来控制从多能性到分化的转变。

Antagonistic pleiotropy and p53

拮抗性多效性和p53