日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Biomolecular condensates sustain pH gradients at equilibrium through charge neutralization

生物分子凝聚体通过电荷中和作用在平衡状态下维持pH梯度。

Ausserwöger, Hannes; Scrutton, Rob; Fischer, Charlotte M; Sneideris, Tomas; Qian, Daoyuan; de Csilléry, Ella; Baronaite, Ieva; Saar, Kadi L; Białek, Alan Z; Oeller, Marc; Krainer, Georg; Franzmann, Titus M; Wittmann, Sina; Iglesias-Artola, Juan M; Invernizzi, Gaetano; Hyman, Anthony A; Alberti, Simon; Lorenzen, Nikolai; Knowles, Tuomas P J

Reversibility and β-sheet formation are decoupled in tau condensate aging

在 tau 凝聚体老化过程中,可逆性和 β 折叠的形成是解耦的。

Fischer, Charlotte M; Edu, Irina A; Šneideris, Tomas; Baronaite, Ieva; Toprakcioglu, Zenon; Deck, Leif-Thore; Qian, Daoyuan; Scrutton, Rob; Dreyer, Lasse; Wen, Jitao; Otzen, Daniel E; Wu, Si; Perrett, Sarah; Knowles, Tuomas P J

Expanding the substrate scope of a bacterial monoterpene synthase for the production of sesquiterpenoid and diterpenoid products

拓展细菌单萜合酶的底物范围,用于生产倍半萜和二萜类化合物

Nicole G H Leferink,Joshua N Whitehead,Linus O Johannissen,Nigel S Scrutton

Abstraction hierarchy to define biofoundry workflows and operations for interoperable synthetic biology research and applications

用于定义生物铸造工作流程和操作的抽象层次结构,以实现可互操作的合成生物学研究和应用。

Kim, Haseong; Hillson, Nathan J; Cho, Byung-Kwan; Sung, Bong Hyun; Lee, Dae-Hee; Kim, Dong-Myung; Oh, Min-Kyu; Chang, Matthew Wook; Jin, Yong-Su; Rosser, Susan J; Vegh, Peter; Fragkoudis, Rennos; Le Feuvre, Rosalind; Scrutton, Nigel S; Storch, Marko; Seong, Wonjae; Freemont, Paul S; Lee, Seung-Goo

Asymmetric Enantio-complementary Synthesis of Thioethers via Ene-Reductase-Catalyzed C-C Bond Formation

通过烯还原酶催化的C-C键形成实现硫醚的不对称对映体互补合成

Heckmann, Christian M; Heyes, Derren J; Pabst, Martin; Otten, Edwin; Scrutton, Nigel S; Paul, Caroline E

Exploring the Increased Activity of the Blue Light-Dependent Photoenzyme Fatty Acid Photodecarboxylase under Violet Light

探索紫光照射下蓝光依赖性光酶脂肪酸光脱羧酶活性增强的现象

Spacey, Harry J; Healy, Daniel; Kalapothakis, Jason M D; Ma, Junfeng; Sakuma, Michiyo; Barran, Perdita E; Heyes, Derren J; Scrutton, Nigel S

Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen.

细胞外相分离介导甲状腺滤泡腔内甲状腺球蛋白的储存和释放

Yao Yihan, Erkamp Nadia, Sneideris Tomas, Yang Xiqiao, Scrutton Rob, Schneider Matthias M, Fischer Charlotte M, Schoenmakers Erik, Schoenmakers Nadia, Knowles Tuomas P J

A parallel bioreactor strategy to rapidly determine growth-coupling relationships for bioproduction: a mevalonate case study

利用平行生物反应器策略快速确定生物生产中的生长耦合关系:以甲羟戊酸为例

Banner, Alec; Webb, Joseph; Scrutton, Nigel

Enhanced bioproduction and processing of mandelic acid enantiomers: towards a sustainable platform for high-value pharmaceutical and polymer applications

提高扁桃酸对映体的生物生产和加工效率:构建高价值药物和聚合物应用的可持续平台

Messiha, Hanan Latif; Banner, Alec; Amer, Mohamed; Robinson, Christopher James; Alwattar, Aula; Tilakaratna, Viranga; Le Feuvre, Rosalind; Scrutton, Nigel Shaun

De Novo Production of Xanthohumol by a Metabolically Engineered Escherichia coli

利用代谢工程改造的大肠杆菌从头生产黄腐酚

Gomes, Daniela; Santos, Joana; Venâncio, Armando; Rodrigues, Joana L; Scrutton, Nigel S; Rodrigues, Ligia R