Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity
全基因组遗传合成致死分析表明 CDK12 是 PARP1/2 抑制剂敏感性的新决定因素
期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-13-2541
Ilirjana Bajrami, Jessica R Frankum, Asha Konde, Rowan E Miller, Farah L Rehman, Rachel Brough, James Campbell, David Sims, Rumana Rafiq, Sean Hooper, Lina Chen, Iwanka Kozarewa, Ioannis Assiotis, Kerry Fenwick, Rachael Natrajan, Christopher J Lord, Alan Ashworth
