日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Addressing the pathophysiology of venous thrombosis and chronic kidney disease in sickle cell trait using a mouse model.

利用小鼠模型探讨镰状细胞性状中静脉血栓形成和慢性肾脏疾病的病理生理学

Trebak Fatima, Sako Mohammad O, Grover Steven P, Seanoon Karnsasin, Pawlinski Izabela, Moonla Chatphatai, Henderson Michael W, Derebail Vimal K, Monroe Dougald M, Ellsworth Patrick, Pawlinski Rafal, Kasztan Malgorzata, Key Nigel S

Site-directed mutagenesis of tissue factor pathway inhibitor-binding exosite D60A on factor VII results in a new factor VII variant with lower coagulant activity

对因子VII上组织因子途径抑制剂结合位点D60A进行定点诱变,可产生一种凝血活性较低的新型因子VII变体。

Seanoon, Karnsasin; Kitiyanant, Vorawat; Payongsri, Panwajee; Sirachainan, Nongnuch; Angchaisuksiri, Pantep; Chuansumrit, Ampaiwan; Hongeng, Suradej; Tanratana, Pansakorn

Mutations of TFPI-binding exosites on factor VII cause bleeding phenotypes in factor VII deficiency

因子VII上TFPI结合位点的突变会导致因子VII缺乏症患者出现出血表型。

Seanoon, Karnsasin; Payongsri, Panwajee; Vivithanaporn, Pornpun; Sirachainan, Nongnuch; Chuansumrit, Ampaiwan; Hongeng, Suradej; Tanratana, Pansakorn