日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Let-7 restrains an epigenetic circuit in AT2 cells to prevent fibrogenic intermediates in pulmonary fibrosis

Let-7抑制AT2细胞中的表观遗传回路,从而阻止肺纤维化中纤维化中间体的产生

Matthew J Seasock # ,Md Shafiquzzaman # ,Maria E Ruiz-Echartea ,Rupa S Kanchi ,Brandon T Tran ,Lukas M Simon ,Matthew D Meyer ,Phillip A Erice ,Shivani L Lotlikar ,Stephanie C Wenlock ,Scott A Ochsner ,Anton Enright ,Alex F Carisey ,Freddy Romero ,Ivan O Rosas ,Katherine Y King ,Neil J McKenna ,Cristian Coarfa ,Antony Rodriguez

Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORγt

Mirlet7 miRNA家族的下调通过解除RORγt的抑制促进Tc17细胞分化和肺气肿。

Erice, Phillip A; Huang, Xinyan; Seasock, Matthew J; Robertson, Matthew J; Tung, Hui-Ying; Perez-Negron, Melissa A; Lotlikar, Shivani L; Corry, David B; Kheradmand, Farrah; Rodriguez, Antony

Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt

Let-7 miRNA 的下调通过解除 RORγt 的抑制作用促进 Tc17 细胞分化和肺气肿。

Erice, Phillip A; Huang, Xinyan; Seasock, Matthew J; Robertson, Matthew J; Tung, Hui-Ying; Perez-Negron, Melissa A; Lotlikar, Shivani L; Corry, David B; Kheradmand, Farrah; Rodriguez, Antony

Let-7 restrains an oncogenic epigenetic circuit in AT2 cells to prevent ectopic formation of fibrogenic transitional cell intermediates and pulmonary fibrosis

Let-7 抑制 AT2 细胞中的致癌表观遗传回路,以防止异位形成纤维化过渡细胞中间体和肺纤维化

Matthew J Seasock, Md Shafiquzzaman, Maria E Ruiz-Echartea, Rupa S Kanchi, Brandon T Tran, Lukas M Simon, Matthew D Meyer, Phillip A Erice, Shivani L Lotlikar, Stephanie C Wenlock, Scott A Ochsner, Anton Enright, Alex F Carisey, Freddy Romero, Ivan O Rosas, Katherine Y King, Neil J McKenna, Cristian

Host gastric corpus microenvironment facilitates Ascaris suum larval hatching and infection in a murine model

宿主胃体微环境促进小鼠模型中猪蛔虫幼虫孵化和感染

Yifan Wu, Grace Adeniyi-Ipadeola, Mahliyah Adkins-Threats, Matthew Seasock, Charlie Suarez-Reyes, Ricardo Fujiwara, Maria Elena Bottazzi, Lizhen Song, Jason C Mills, Jill E Weatherhead

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

将人类特征的遗传结构映射到肾脏中的细胞类型可以确定疾病的机制和潜在的治疗方法

Xin Sheng #, Yuting Guan #, Ziyuan Ma, Junnan Wu, Hongbo Liu, Chengxiang Qiu, Steven Vitale, Zhen Miao, Matthew J Seasock, Matthew Palmer, Myung K Shin, Kevin L Duffin, Steven S Pullen, Todd L Edwards, Jacklyn N Hellwege, Adriana M Hung, Mingyao Li, Benjamin F Voight, Thomas M Coffman, Christopher D

The key role of NLRP3 and STING in APOL1-associated podocytopathy

NLRP3 和 STING 在 APOL1 相关足细胞病中的关键作用

Junnan Wu, Archana Raman, Nathan J Coffey, Xin Sheng, Joseph Wahba, Matthew J Seasock, Ziyuan Ma, Pazit Beckerman, Dorottya Laczkó, Matthew B Palmer, Jeffrey B Kopp, Jay J Kuo, Steven S Pullen, Carine M Boustany-Kari, Andreas Linkermann, Katalin Susztak

Genome-wide association studies identify the role of caspase-9 in kidney disease

全基因组关联研究确定了 caspase-9 在肾脏疾病中的作用

Tomohito Doke, Shizheng Huang, Chengxiang Qiu, Xin Sheng, Matthew Seasock, Hongbo Liu, Ziyuan Ma, Matthew Palmer, Katalin Susztak

Functional methylome analysis of human diabetic kidney disease

人类糖尿病肾病的功能性甲基化组分析

Park, Jihwan; Guan, Yuting; Sheng, Xin; Gluck, Caroline; Seasock, Matthew J; Hakimi, A Ari; Qiu, Chengxiang; Pullman, James; Verma, Amit; Li, Hongzhe; Palmer, Matthew; Susztak, Katalin

Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease

肾脏区域特异性遗传变异分析确定了慢性肾脏疾病的新途径

Chengxiang Qiu, Shizheng Huang, Jihwan Park, YoSon Park, Yi-An Ko, Matthew J Seasock, Joshua S Bryer, Xiang-Xi Xu, Wen-Chao Song, Matthew Palmer, Jon Hill, Paolo Guarnieri, Julie Hawkins, Carine M Boustany-Kari, Steven S Pullen, Christopher D Brown, Katalin Susztak