日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lineage specification in glioblastoma is regulated by METTL7B

胶质母细胞瘤的谱系分化受METTL7B调控

Myrianni Constantinou,James Nicholson,Xinyu Zhang,Eleni Maniati,Sara Lucchini,Gabriel Rosser,Claire Vinel,Jun Wang,Yau Mun Lim,Sebastian Brandner,Sven Nelander,Sara Badodi,Silvia Marino

Recurrent adamantinomatous craniopharyngiomas show MAPK pathway activation, clonal evolution and rare TP53-loss-mediated malignant progression

复发性釉质瘤性颅咽管瘤表现出 MAPK 通路激活、克隆进化和罕见的 TP53 缺失介导的恶性进展

John R Apps, Jose Mario Gonzalez-Meljem, Romain Guiho, Jessica C Pickles, Eric Prince, Edward Schwalbe, Nikhil Joshi, Thomas J Stone, Olumide Ogunbiyi, Jane Chalker, Akang Bassey, Georg Otto, Rosalind Davies, Debbie Hughes, Sebastian Brandner, Enrica Tan, Victoria Lee, Caroline Hayhurst, Cassie Klin

Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob disease risk gene Stx6

散发性克雅氏病风险基因 Stx6 遗传减少的小鼠的特征和朊病毒传播研究

Emma Jones, Elizabeth Hill, Jacqueline Linehan, Tamsin Nazari, Adam Caulder, Gemma F Codner, Marie Hutchison, Matthew Mackenzie, Michael Farmer, Thomas Coysh, Michael Wiggins De Oliveira, Huda Al-Doujaily, Malin Sandberg, Emmanuelle Viré, Thomas J Cunningham, Emmanuel A Asante, Sebastian Brandner, J

Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomas

CDKN2A mRNA 表达增加是临床侵袭性脑膜瘤的转录组标记

Justin Z Wang, Vikas Patil, Jeff Liu, Helin Dogan, Ghazaleh Tabatabai, Leeor S Yefet, Felix Behling, Elgin Hoffman, Severa Bunda, Rebecca Yakubov, Ramneet Kaloti, Sebastian Brandner, Andrew Gao, Aaron Cohen-Gadol, Jill Barnholtz-Sloan, Marco Skardelly, Marcos Tatagiba, David R Raleigh, Felix Sahm, P

Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes

具有不良临床结果和非典型组织病理学特征的神经节胶质瘤被定义为 PTPN11/KRAS/NF1 和其他 RAS-/MAP-Kinase 通路基因的改变

Lucas Hoffmann, Roland Coras, Katja Kobow, Javier A López-Rivera, Dennis Lal, Costin Leu, Imad Najm, Peter Nürnberg, Jochen Herms, Patrick N Harter, Christian G Bien, Thilo Kalbhenn, Markus Müller, Tom Pieper, Till Hartlieb, Manfred Kudernatsch, Hajo Hamer, Sebastian Brandner, Karl Rössler, Ingmar B

Deep histopathology genotype-phenotype analysis of focal cortical dysplasia type II differentiates between the GATOR1-altered autophagocytic subtype IIa and MTOR-altered migration deficient subtype IIb

局灶性皮质发育不良 II 型的深度组织病理学基因型-表型分析区分了 GATOR1 改变的自噬亚型 IIa 和 MTOR 改变的迁移缺陷亚型 IIb

Jonas Honke, Lucas Hoffmann, Roland Coras, Katja Kobow, Costin Leu, Tom Pieper, Till Hartlieb, Christian G Bien, Friedrich Woermann, Thomas Cloppenborg, Thilo Kalbhenn, Ahmed Gaballa, Hajo Hamer, Sebastian Brandner, Karl Rössler, Arnd Dörfler, Stefan Rampp, Johannes R Lemke, Sara Baldassari, Stéphan

Diagnostic test accuracy and cost-effectiveness of tests for codeletion of chromosomal arms 1p and 19q in people with glioma

胶质瘤患者 1p 和 19q 染色体组缺失检测的诊断准确性和成本效益

Alexandra McAleenan, Hayley E Jones, Ashleigh Kernohan, Tomos Robinson, Lena Schmidt, Sarah Dawson, Claire Kelly, Emmelyn Spencer Leal, Claire L Faulkner, Abigail Palmer, Christopher Wragg, Sarah Jefferies, Sebastian Brandner, Luke Vale, Julian Pt Higgins, Kathreena M Kurian

Global hypo-methylation in a proportion of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape

在富含星形胶质细胞特征的胶质母细胞瘤中,部分肿瘤细胞的低甲基化与侵袭性增强和免疫微环境改变相关。

James Boot ,Gabriel Rosser ,Dailya Kancheva ,Claire Vinel ,Yau Mun Lim ,Nicola Pomella ,Xinyu Zhang ,Loredana Guglielmi ,Denise Sheer ,Michael Barnes ,Sebastian Brandner ,Sven Nelander ,Kiavash Movahedi ,Silvia Marino

Multisystem screening reveals SARS-CoV-2 in neurons of the myenteric plexus and in megakaryocytes

多系统筛查发现 SARS-CoV-2 存在于肌间神经丛神经元和巨核细胞中

Sandra Gray-Rodriguez, Melanie P Jensen, Maria Otero-Jimenez, Brian Hanley, Olivia C Swann, Patrick A Ward, Francisco J Salguero, Nadira Querido, Ildiko Farkas, Elisavet Velentza-Almpani, Justin Weir, Wendy S Barclay, Miles W Carroll, Zane Jaunmuktane, Sebastian Brandner, Ute Pohl, Kieren Allinson, 

Phenotyping clonal populations of glioma stem cell reveals a high degree of plasticity in response to changes of microenvironment

胶质瘤干细胞克隆群的表型分析表明,其对微环境变化具有高度的可塑性

James A Innes, Andrew S Lowe, Raquel Fonseca, Natasha Aley, Tedani El-Hassan, Myrianni Constantinou, Joanne Lau, Ayad Eddaoudi, Silvia Marino, Sebastian Brandner