日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Microcephaly-associated protein WDR62 supports purine metabolism by interacting with co-chaperone BAG2.

与小头畸形相关的蛋白质 WDR62 通过与辅助伴侣 BAG2 相互作用来支持嘌呤代谢。

Morris Matthew J, Yeap Yvonne Y, Edwards Jonathon R, Chen Chi, Paolino Annalisa, Furness Sebastian G B, Millard S Sean, Pagan Julia K, Fenlon Laura R, Ng Dominic C H

Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling

型胆囊收缩素受体构象的胆固醇依赖性动态变化影响配体结合和 G 蛋白偶联

Kaleeckal G Harikumar, Peishen Zhao, Brian P Cary, Xiaomeng Xu, Aditya J Desai, Maoqing Dong, Jesse I Mobbs, Chirine Toufaily, Sebastian G B Furness, Arthur Christopoulos, Matthew J Belousoff, Denise Wootten, Patrick M Sexton, Laurence J Miller

Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre

啮齿动物腰骶排便中心多巴胺、生长素释放肽和血清素受体的结肠运动部位和作用机制

Mitchell T Ringuet, Ada Koo, Sebastian G B Furness, Stuart J McDougall, John B Furness

Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity

与 Gs 和 Gq 模拟蛋白结合的人类胆囊收缩素 1 (CCK1) 受体的结构有助于深入了解 G 蛋白选择性的机制

Jesse I Mobbs, Matthew J Belousoff, Kaleeckal G Harikumar, Sarah J Piper, Xiaomeng Xu, Sebastian G B Furness, Hari Venugopal, Arthur Christopoulos, Radostin Danev, Denise Wootten, David M Thal, Laurence J Miller, Patrick M Sexton

Structure and dynamics of the active Gs-coupled human secretin receptor

活性 Gs 偶联人类促胰液素受体的结构和动力学

Maoqing Dong #, Giuseppe Deganutti #, Sarah J Piper #, Yi-Lynn Liang #, Maryam Khoshouei #, Matthew J Belousoff, Kaleeckal G Harikumar, Christopher A Reynolds, Alisa Glukhova, Sebastian G B Furness, Arthur Christopoulos, Radostin Danev, Denise Wootten, Patrick M Sexton, Laurence J Miller

Structure and Dynamics of Adrenomedullin Receptors AM1 and AM2 Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins

肾上腺髓质素受体 AM1 和 AM2 的结构和动力学揭示了受体活性修饰蛋白控制受体表型的关键机制

Yi-Lynn Liang, Matthew J Belousoff, Madeleine M Fletcher, Xin Zhang, Maryam Khoshouei, Giuseppe Deganutti, Cassandra Koole, Sebastian G B Furness, Laurence J Miller, Debbie L Hay, Arthur Christopoulos, Christopher A Reynolds, Radostin Danev, Denise Wootten, Patrick M Sexton

Building the case for the calcitonin receptor as a viable target for the treatment of glioblastoma

论证降钙素受体作为胶质母细胞瘤治疗的可行靶点

Gupta, Pragya; Furness, Sebastian G B; Bittencourt, Lucas; Hare, David L; Wookey, Peter J

The Molecular Control of Calcitonin Receptor Signaling

降钙素受体信号传导的分子控制

Emma Dal Maso, Alisa Glukhova, Yue Zhu, Javier Garcia-Nafria, Christopher G Tate, Silvia Atanasio, Christopher A Reynolds, Erney Ramírez-Aportela, Jose-Maria Carazo, Caroline A Hick, Sebastian G B Furness, Debbie L Hay, Yi-Lynn Liang, Laurence J Miller, Arthur Christopoulos, Ming-Wei Wang, Denise Wo

TrkB Agonist LM22A-4 Increases Oligodendroglial Populations During Myelin Repair in the Corpus Callosum

TrkB 激动剂 LM22A-4 在胼胝体髓鞘修复过程中增加少突胶质细胞数量

Huynh T H Nguyen, Rhiannon J Wood, Alexa R Prawdiuk, Sebastian G B Furness, Junhua Xiao, Simon S Murray, Jessica L Fletcher

Expression and activity of the calcitonin receptor family in a sample of primary human high-grade gliomas

降钙素受体家族在人类原发性高级别胶质瘤样本中的表达和活性

Anna Ostrovskaya, Caroline Hick, Dana S Hutchinson, Brett W Stringer, Peter J Wookey, Denise Wootten, Patrick M Sexton, Sebastian G B Furness