日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In Vitro/In Vivo Translation of Synergistic Combination of MDM2 and MEK Inhibitors in Melanoma Using PBPK/PD Modelling: Part II

使用 PBPK/PD 模型对黑色素瘤中 MDM2 和 MEK 抑制剂协同组合进行体外/体内转化:第二部分

Jakub Witkowski, Sebastian Polak, Zbigniew Rogulski, Dariusz Pawelec

In Vitro/In Vivo Translation of Synergistic Combination of MDM2 and MEK Inhibitors in Melanoma Using PBPK/PD Modelling: Part I

使用 PBPK/PD 模型对黑色素瘤中 MDM2 和 MEK 抑制剂协同组合进行体外/体内转化:第一部分

Jakub Witkowski, Sebastian Polak, Zbigniew Rogulski, Dariusz Pawelec

Model-Based Approach for Optimizing Ceftobiprole Dosage in Pediatric Patients

基于模型的儿童患者头孢吡肟剂量优化方法

Rubino, Christopher M; Cammarata, Anthony P; Smits, Anne; Schröpf, Sebastian; Polak, Mark; Litherland, Karine; Hamed, Kamal

Combining an in silico proarrhythmic risk assay with a tPKPD model to predict QTc interval prolongation in the anesthetized guinea pig assay

将计算机模拟心律失常风险检测与 tPKPD 模型相结合,预测麻醉豚鼠检测中的 QTc 间期延长

Pierre Morissette, Sebastian Polak, Anne Chain, Jin Zhai, John P Imredy, Mary Jo Wildey, Jeffrey Travis, Kevin Fitzgerald, Patrick Fanelli, Elisa Passini, Blanca Rodriguez, Frederick Sannajust, Christopher Regan

Characterization of In Vitro and In Vivo Metabolism of Antazoline Using Liquid Chromatography-Tandem Mass Spectrometry

使用液相色谱-串联质谱法表征安他唑啉的体内和体外代谢

Joanna Giebułtowicz, Natalia Korytowska, Roman Piotrowski, Piotr Kułakowski, Gniewomir Latacz, Ewa Szymańska, Barbara Wiśniowska, Sebastian Polak