日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis

AMPKα2的缺失促进黑色素瘤的生长和脑转移

Ping Yuan, Da Teng, Evelyn de Groot, Man Li, Sebastian Trousil, Che-Hung Shen, Jason Roszik, Michael A Davies, Y N Vashisht Gopal, Bin Zheng

Integrated analysis of multiple receptor tyrosine kinases identifies Axl as a therapeutic target and mediator of resistance to sorafenib in hepatocellular carcinoma

多种受体酪氨酸激酶的综合分析确定 Axl 是肝细胞癌的治疗靶点和对索拉非尼耐药的介质

David J Pinato, Matthew W Brown, Sebastian Trousil, Eric O Aboagye, Jamie Beaumont, Hua Zhang, Helen M Coley, Francesco A Mauri, Rohini Sharma

Development and Evaluation of an 18F-Radiolabeled Monocyclam Derivative for Imaging CXCR4 Expression

18F-放射性标记的单环酰胺衍生物的开发和评估,用于成像 CXCR4 表达

Diana Brickute, Marta Braga, Maciej A Kaliszczak, Chris Barnes, Doreen Lau, Laurence Carroll, Elizabeth Stevens, Sebastian Trousil, Israt S Alam, Quang-Dé Nguyen, Eric O Aboagye

Phenformin Enhances the Efficacy of ERK Inhibition in NF1-Mutant Melanoma

苯乙双胍增强 ERK 抑制对 NF1 突变型黑色素瘤的疗效

Sebastian Trousil, Shuang Chen, Chan Mu, Fiona M Shaw, Zhan Yao, Yuping Ran, Tiwari Shakuntala, Taha Merghoub, Dieter Manstein, Neal Rosen, Lewis C Cantley, Jonathan H Zippin, Bin Zheng

Programmed cell death ligands expression in phaeochromocytomas and paragangliomas: Relationship with the hypoxic response, immune evasion and malignant behavior

嗜铬细胞瘤和副神经节瘤中程序性细胞死亡配体的表达:与缺氧反应、免疫逃避和恶性行为的关系

David J Pinato, James R Black, Sebastian Trousil, Roberto E Dina, Pritesh Trivedi, Francesco A Mauri, Rohini Sharma

Loss of cohesin complex components STAG2 or STAG3 confers resistance to BRAF inhibition in melanoma

黏连蛋白复合物成分 STAG2 或 STAG3 的缺失导致黑色素瘤对 BRAF 抑制产生抗性

Che-Hung Shen, Sun Hye Kim, Sebastian Trousil, Dennie T Frederick, Adriano Piris, Ping Yuan, Li Cai, Lei Gu, Man Li, Jung Hyun Lee, Devarati Mitra, David E Fisher, Ryan J Sullivan, Keith T Flaherty, Bin Zheng

The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth

新型胆碱激酶抑制剂ICL-CCIC-0019可重编程细胞代谢并抑制癌细胞生长

Sebastian Trousil, Maciej Kaliszczak, Zachary Schug, Quang-De Nguyen, Giampaolo Tomasi, Rosy Favicchio, Diana Brickute, Robin Fortt, Frazer J Twyman, Laurence Carroll, Andrew Kalusa, Naveenan Navaratnam, Thomas Adejumo, David Carling, Eyal Gottlieb, Eric O Aboagye