The hinge-engineered IgG1-IgG3 hybrid subclass IgGh47 potently enhances Fc-mediated function of anti-streptococcal and SARS-CoV-2 antibodies
铰链工程化的 IgG1-IgG3 混合亚类 IgGh47 可有效增强 Fc 介导的抗链球菌和 SARS-CoV-2 抗体的功能
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-024-47928-8
Arman Izadi, Yasaman Karami, Eleni Bratanis, Sebastian Wrighton, Hamed Khakzad, Maria Nyblom, Berit Olofsson, Lotta Happonen, Di Tang, Martin Sundwall, Magdalena Godzwon, Yashuan Chao, Alejandro Gomez Toledo, Tobias Schmidt, Mats Ohlin, Michael Nilges, Johan Malmström, Wael Bahnan, Oonagh Shannon, L
代谢
信号转导
免疫
心血管
新冠
Goat
IgG F(ab')2
