Ablation of prostaglandin E(2) signalling through dual receptor knockout in CAR T cells enhances therapeutic efficacy in solid tumours
通过CAR T细胞中的双受体敲除消除前列腺素E(2)信号传导可增强实体瘤的治疗效果
期刊:Nature Biomedical Engineering
影响因子:26.6
doi:10.1038/s41551-025-01610-6
Dörr, Janina; Gregor, Lisa; Lacher, Sebastian B; Oner, Arman; Sun, Yi; Piseddu, Ignazio; Fertig, Luisa; Spajic, Sebastijan; Lesch, Stefanie; Michaelides, Stefanos; Seifert, Matthias; Gottschlich, Adrian; Samson, Natasha; Majed, Lina; Briukhovetska, Daria; Simnica, Donjetë; Hartmann, Viktoria; Gabriel, Kathrin; Cohen, Sonia; Boland, Genevieve M; Andreu-Sanz, David; Carlini, Emanuele; Stock, Sophia; Holtermann, Anne; Müller, Philipp Jie; Strzalkowski, Thaddäus; Trefny, Marcel P; Endres, Stefan; Jenkins, Russell W; Böttcher, Jan P; Kobold, Sebastian
