日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bordetella adenylate cyclase toxin elicits chromatin remodeling and transcriptional reprogramming that blocks differentiation of monocytes into macrophages.

博德特氏菌腺苷酸环化酶毒素可引起染色质重塑和转录重编程,从而阻止单核细胞分化为巨噬细胞

Ahmad Jawid Nazir, Modrak Martin, Fajfrova Marketa, Sotoca Blanca Martin-Borja, Benada Oldrich, Sebo Peter

Acyl chains stabilize the acylated domain and determine the receptor-mediated interaction of the Bordetella adenylate cyclase toxin with cell membrane

酰基链稳定酰化结构域,并决定博德特氏菌腺苷酸环化酶毒素与细胞膜的受体介导相互作用。

Espinosa-Vinals, Carlos; Stransky, Jan; Osicka, Radim; Osickova, Adriana; Jurnecka, David; Sebo, Peter; Bumba, Ladislav

Intranasal application of a bifunctional pertactin-RTX fusion antigen elicits protection of mouse airway mucosa against Bordetella pertussis colonization

鼻内应用双功能百日咳杆菌素-RTX融合抗原可保护小鼠气道黏膜免受百日咳杆菌定植

Espinosa-Vinals, Carlos; Holubova, Jana; Stanek, Ondrej; Osicka, Radim; Masin, Jiri; Arellano Herencia, Fresia Esther; Sebo, Peter

Highlights of the 14th International Bordetella Symposium

第十四届国际博德特氏菌研讨会亮点

Munoz Navarrete, Kevin; Edwards, Kathryn M; Mills, Kingston H G; Kamanová, Jana; Rodriguez, María Eugenia; Gorringe, Andrew; Preston, Andrew; Kampmann, Beate; Gestal, Monica C; Harvill, Eric T; Dubey, Purnima; Diavatopoulos, Dimitri A; Mattoo, Seema; Scanlon, Karen M; Locht, Camille; Sebo, Peter

A whole-cell pertussis vaccine engineered to elicit reduced reactogenicity protects baboons against pertussis challenge

一种经过基因工程改造、可降低反应原性的全细胞百日咳疫苗能够保护狒狒免受百日咳病毒攻击。

Kapil, Parul; Wang, Yihui; Gregg, Kelsey; Zimmerman, Lindsey; Molano, Damaris; Maldonado Villeda, Jonatan; Sebo, Peter; Merkel, Tod J

A conserved tryptophan in the acylated segment of RTX toxins controls their β(2) integrin-independent cell penetration

RTX毒素酰化片段中一个保守的色氨酸残基控制着其不依赖于β2整合素的细胞穿透能力。

Osickova, Adriana; Knoblochova, Sarka; Bumba, Ladislav; Man, Petr; Kalaninova, Zuzana; Lepesheva, Anna; Jurnecka, David; Cizkova, Monika; Biedermannova, Lada; Goldsmith, Jory A; Maynard, Jennifer A; McLellan, Jason S; Osicka, Radim; Sebo, Peter; Masin, Jiri

The adenylate cyclase toxin RTX domain follows a series templated folding mechanism with implications for toxin activity

腺苷酸环化酶毒素RTX结构域遵循一系列模板化的折叠机制,这对毒素活性具有重要意义。

Chen, Guojun; Wang, Han; Bumba, Ladislav; Masin, Jiri; Sebo, Peter; Li, Hongbin

The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model

在一种新型小鼠卡他性感染模型中,Fim 和 FhaB 黏附素在鼻腔感染和百日咳杆菌传播中起着至关重要的作用。

Holubova, Jana; Stanek, Ondrej; Juhasz, Attila; Hamidou Soumana, Illiassou; Makovicky, Peter; Sebo, Peter

Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes

百日咳毒素抑制树突状细胞介导的百日咳杆菌向肺引流淋巴结的递送。

Klimova, Nela; Holubova, Jana; Streparola, Gaia; Tomala, Jakub; Brazdilova, Ludmila; Stanek, Ondrej; Bumba, Ladislav; Sebo, Peter

Selective Enhancement of the Cell-Permeabilizing Activity of Adenylate Cyclase Toxin Does Not Increase Virulence of Bordetella pertussis

选择性增强腺苷酸环化酶毒素的细胞通透性活性并不会增加百日咳杆菌的毒力

Holubova, Jana; Juhasz, Attila; Masin, Jiri; Stanek, Ondrej; Jurnecka, David; Osickova, Adriana; Sebo, Peter; Osicka, Radim