日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Preclinical immunogenicity and efficacy of a candidate COVID-19 vaccine based on a vesicular stomatitis virus-SARS-CoV-2 chimera

基于水泡性口炎病毒-SARS-CoV-2 嵌合体的 COVID-19 候选疫苗的临床前免疫原性和有效性

Amy S Espeseth, Maoli Yuan, Michael Citron, Lucia Reiserova, Gavin Morrow, Aaron Wilson, Melanie Horton, Mark Rukhman, Keith Kinek, Fuxiang Hou, Shui L Li, Fengsheng Li, Yesle Choi, Gwen Heidecker, Bin Luo, Guoxin Wu, Lan Zhang, Erica Strable, Joanne DeStefano, Susan Secore, Tarit K Mukhopadhyay, Do

An in vitro culture model to study the dynamics of colonic microbiota in Syrian golden hamsters and their susceptibility to infection with Clostridium difficile

体外培养模型研究叙利亚金黄地鼠结肠菌群动态及其对艰难梭菌感染的敏感性

Matthew Miezeiewski, Todd Schnaufer, Michele Muravsky, Su Wang, Ivette Caro-Aguilar, Susan Secore, David S Thiriot, Charlie Hsu, Irene Rogers, Todd DeSantis, Justin Kuczynski, Alexander J Probst, Christel Chehoud, Rachel Steger, Janet Warrington, Jean-Luc Bodmer, Jon H Heinrichs

Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography

X射线晶体衍射揭示了艰难梭菌毒素B中和抗体贝洛妥珠单抗的作用机制和表位

Orth, Peter; Xiao, Li; Hernandez, Lorraine D; Reichert, Paul; Sheth, Payal R; Beaumont, Maribel; Yang, Xiaoyu; Murgolo, Nicholas; Ermakov, Grigori; DiNunzio, Edward; Racine, Fred; Karczewski, Jerzy; Secore, Susan; Ingram, Richard N; Mayhood, Todd; Strickland, Corey; Therien, Alex G

Development and optimization of a high-throughput assay to measure neutralizing antibodies against Clostridium difficile binary toxin

开发和优化一种高通量检测方法,用于测量针对艰难梭菌二元毒素的中和抗体

Xie, Jinfu; Horton, Melanie; Zorman, Julie; Antonello, Joseph M; Zhang, Yuhua; Arnold, Beth A; Secore, Susan; Xoconostle, Rachel; Miezeiewski, Matthew; Wang, Su; Price, Colleen E; Thiriot, David; Goerke, Aaron; Gentile, Marie-Pierre; Skinner, Julie M; Heinrichs, Jon H

Development and optimization of a novel assay to measure neutralizing antibodies against Clostridium difficile toxins

开发和优化一种用于测量抗艰难梭菌毒素中和抗体的新型检测方法

Xie, Jinfu; Zorman, Julie; Indrawati, Lani; Horton, Melanie; Soring, Keri; Antonello, Joseph M; Zhang, Yuhua; Secore, Susan; Miezeiewski, Matthew; Wang, Su; Kanavage, Anthony D; Skinner, Julie M; Rogers, Irene; Bodmer, Jean-Luc; Heinrichs, Jon H

Selection and characterization of murine monoclonal antibodies to Staphylococcus aureus iron-regulated surface determinant B with functional activity in vitro and in vivo

筛选和鉴定针对金黄色葡萄球菌铁调控表面决定簇B的鼠单克隆抗体,这些抗体在体外和体内均具有功能活性。

Brown, Martha; Kowalski, Rose; Zorman, Julie; Wang, Xin-Min; Towne, Victoria; Zhao, Qinjian; Secore, Susan; Finnefrock, Adam C; Ebert, Tim; Pancari, Greg; Isett, Kevin; Zhang, Yuhua; Anderson, Annaliesa S; Montgomery, Donna; Cope, Leslie; McNeely, Tessie

Serologic assay to quantify human immunoglobulin G antibodies to the Staphylococcus aureus iron surface determinant B antigen

血清学检测定量检测人免疫球蛋白G抗体对金黄色葡萄球菌铁表面决定簇B抗原的水平

Raedler, Michael D; Heyne, Samantha; Wagner, Erica; Shalkowski, Sheri K; Secore, Susan; Anderson, Annaliesa S; Cook, James; Cope, Leslie; McNeely, Tessie; Retzlaff, Mary; Shanter, Jon; Rubinstein, Leonard J; Green, Tina; Kartsonis, N; Esser, Mark T

A novel Staphylococcus aureus vaccine: iron surface determinant B induces rapid antibody responses in rhesus macaques and specific increased survival in a murine S. aureus sepsis model.

一种新型金黄色葡萄球菌疫苗:铁表面决定簇 B 可诱导恒河猴产生快速抗体反应,并在小鼠金黄色葡萄球菌败血症模型中特异性提高存活率

Kuklin Nelly A, Clark Desmond J, Secore Susan, Cook James, Cope Leslie D, McNeely Tessie, Noble Liliane, Brown Martha J, Zorman Julie K, Wang Xin Min, Pancari Gregory, Fan Hongxia, Isett Kevin, Burgess Bruce, Bryan Janine, Brownlow Michelle, George Hugh, Meinz Maria, Liddell Mary E, Kelly Rosemarie, Schultz Loren, Montgomery Donna, Onishi Janet, Losada Maria, Martin Melissa, Ebert Timothy, Tan Charles Y, Schofield Timothy L, Nagy Eszter, Meineke Andreas, Joyce Joseph G, Kurtz Myra B, Caulfield Michael J, Jansen Kathrin U, McClements William, Anderson Annaliesa S