日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts

Wnt信号通路和干细胞数量的基础梯度影响人和小鼠肠道内区域肿瘤的分布。

Leedham, Simon J; Rodenas-Cuadrado, Pedro; Howarth, Kimberley; Lewis, Annabelle; Mallappa, Sreelakshmi; Segditsas, Stefania; Davis, Hayley; Jeffery, Rosemary; Rodriguez-Justo, Manuel; Keshav, Satish; Travis, Simon P L; Graham, Trevor A; East, James; Clark, Susan; Tomlinson, Ian P M

Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1

遗传性混合性息肉综合征是由上游40 kb的重复序列引起的,该重复序列导致BMP拮抗剂GREM1的表达增加和异位表达。

Jaeger, Emma; Leedham, Simon; Lewis, Annabelle; Segditsas, Stefania; Becker, Martin; Cuadrado, Pedro Rodenas; Davis, Hayley; Kaur, Kulvinder; Heinimann, Karl; Howarth, Kimberley; East, James; Taylor, Jenny; Thomas, Huw; Tomlinson, Ian

The C-terminus of Apc does not influence intestinal adenoma development or progression.

Apc 的 C 端不影响肠道腺瘤的发生或发展

Lewis Annabelle, Davis Hayley, Deheragoda Maesha, Pollard Patrick, Nye Emma, Jeffery Rosemary, Segditsas Stefania, East Philip, Poulsom Richard, Stamp Gordon, Wright Nicholas, Tomlinson Ian