日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells.

可诱导的、无病毒的直接谱系重编程增强了人类内耳毛细胞样细胞的可扩展生成

期刊:
影响因子:
doi:10.1101/2025.02.20.639352
Rainey Robert N, Houman Sam D, Menendez Louise, Chang Ryan, Tao Litao, Bugacov Helena, McMahon Andrew P, Kalluri Radha, Oghalai John S, Groves Andrew K, Segil Neil
细胞生物学
Human
血管生成
发表日期：2025
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Long-range Atoh1 enhancers maintain competency for hair cell regeneration in the inner ear

长程Atoh1增强子维持内耳毛细胞再生能力

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2418098121
Shi, Tuo; Kim, Yeeun; Llamas, Juan; Wang, Xizi; Fabian, Peter; Lozito, Thomas P; Segil, Neil; Gnedeva, Ksenia; Crump, J Gage
细胞生物学
发表日期：2024
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SoxC transcription factors shape the epigenetic landscape to establish competence for sensory differentiation in the mammalian organ of Corti

SoxC转录因子塑造表观遗传图谱，从而建立哺乳动物科尔蒂氏器感觉分化的能力。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2301301120
Wang, Xizi; Llamas, Juan; Trecek, Talon; Shi, Tuo; Tao, Litao; Makmura, Welly; Crump, J Gage; Segil, Neil; Gnedeva, Ksenia
表观遗传
发表日期：2023
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CDK2 regulates aminoglycoside-induced hair cell death through modulating c-Jun activity: Inhibiting CDK2 to preserve hearing

CDK2通过调节c-Jun活性来调控氨基糖苷类抗生素诱导的毛细胞死亡：抑制CDK2可保护听力

期刊:Frontiers in Molecular Neuroscience
影响因子:3.8
doi:10.3389/fnmol.2022.1013383
Tao, Litao; Segil, Neil
信号转导
细胞生物学
c-Jun
CDK2
发表日期：2022
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Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates

Notch信号的精细调控决定了科尔蒂氏器的边界，并决定了感觉细胞的命运。

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.19921
Basch, Martin L; Brown, Rogers M 2nd; Jen, Hsin-I; Semerci, Fatih; Depreux, Frederic; Edlund, Renée K; Zhang, Hongyuan; Norton, Christine R; Gridley, Thomas; Cole, Susan E; Doetzlhofer, Angelika; Maletic-Savatic, Mirjana; Segil, Neil; Groves, Andrew K
信号转导
细胞生物学
Notch
发表日期：2016
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Nucleocytoplasmic connections and deafness

核质连接与耳聋

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI67454
Worman, Howard J; Segil, Neil
发表日期：2013
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Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti

FGF对Hey2的调控提供了一种不依赖于Notch信号的机制，用于维持科尔蒂氏器中柱状细胞的命运。

期刊:Developmental Cell
影响因子:8.7
doi:10.1016/j.devcel.2008.11.008
Doetzlhofer, Angelika; Basch, Martin L; Ohyama, Takahiro; Gessler, Manfred; Groves, Andrew K; Segil, Neil
信号转导
细胞生物学
Notch
发表日期：2009
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Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation

Dishevelled基因介导哺乳动物保守的PCP通路，从而调控神经胚形成过程中的趋同延伸。

期刊:Development
影响因子:3.6
doi:10.1242/dev.02347
Wang, Jianbo; Hamblet, Natasha S; Mark, Sharayne; Dickinson, Mary E; Brinkman, Brendan C; Segil, Neil; Fraser, Scott E; Chen, Ping; Wallingford, John B; Wynshaw-Boris, Anthony
信号转导
发表日期：2006
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Expression of Islet1 marks the sensory and neuronal lineages in the mammalian inner ear

Islet1的表达标志着哺乳动物内耳中的感觉和神经谱系。

期刊:Journal of Comparative Neurology
影响因子:2.1
doi:10.1002/cne.20257
Radde-Gallwitz, Kristen; Pan, Ling; Gan, Lin; Lin, Xi; Segil, Neil; Chen, Ping
发表日期：2004
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