AS04 drives superior cross-protective antibody response by increased NOTCH signaling of dendritic cells and proliferation of memory B cells
AS04 通过增强树突状细胞的 NOTCH 信号传导和促进记忆 B 细胞增殖,从而驱动更强的交叉保护性抗体反应。
期刊:Frontiers in Immunology
影响因子:
doi:10.3389/fimmu.2025.1623405
D'Onofrio, Valentino; Santana, Ana Carolina; Pauwels, Marthe; Waerlop, Gwenn; Willems, Anthony; De Boever, Fien; Müller, Martin; Sehr, Peter; Waterboer, Tim; Leroux-Roels, Isabel; Sharma, Ashish A; Sékaly, Rafick Pierre; Leroux-Roels, Geert
T细胞
OTC
NOTCH
信号转导
树突状细胞
细胞生物学
树突状细胞
免疫/内分泌