日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Enzyme-Responsive Cyclic Gapmer Antisense Oligonucleotides via Thymidine C5-C5 Cross-Linking within the Gap Region Using a Galactosylated Branched Self-Immolative Linker

利用半乳糖基化分支自裂解连接子，通过胸苷C5-C5交联在间隙区构建酶响应性环状间隙反义寡核苷酸

期刊:Bioconjugate Chemistry
影响因子:3.9
doi:10.1021/acs.bioconjchem.6c00065
Miyaji, Kento; Habu, Narumi; Seio, Kohji
发表日期：2026
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Topological Switch-OFF and β-Galactosidase-Triggered Switch-ON of Cyclic Antisense Oligonucleotides via CuAAC for Controlled RNA Cleavage

利用 CuAAC 实现环状反义寡核苷酸的拓扑关闭和 β-半乳糖苷酶触发的开启，从而控制 RNA 切割

期刊:Bioconjugate Chemistry
影响因子:3.9
doi:10.1021/acs.bioconjchem.5c00295
Miyaji, Kento; Takeuchi, Keita; Seio, Kohji
发表日期：2025
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Hic-5 antisense oligonucleotide inhibits advanced hepatic fibrosis and steatosis in vivo

Hic-5反义寡核苷酸在体内抑制晚期肝纤维化和脂肪变性

期刊:Jhep Reports
影响因子:7.5
doi:10.1016/j.jhepr.2024.101195
Noguchi, Masahito; Miyauchi, Aya; Masaki, Yoshiaki; Sakaki, Masashi; Lei, Xiao-Feng; Kobayashi-Tanabe, Momoko; Miyazaki, Akira; Aoki, Takeshi; Yoshida, Hitoshi; Seio, Kohji; Kim-Kaneyama, Joo-Ri
发表日期：2024
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Influence of the Hypoxia-Activated Prodrug Evofosfamide (TH-302) on Glycolytic Metabolism of Canine Glioma: A Potential Improvement in Cancer Metabolism

缺氧激活前药Evofosfamide (TH-302)对犬神经胶质瘤糖酵解代谢的影响：癌症代谢的潜在改善

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers15235537
Yamazaki, Hiroki; Onoyama, Seio; Gotani, Shunichi; Deguchi, Tatsuya; Tamura, Masahiro; Ohta, Hiroshi; Iwano, Hidetomo; Nishida, Hidetaka; Dickinson, Peter J; Akiyoshi, Hideo
肿瘤
肿瘤免疫
神经科学
代谢
胶质瘤
Canine
发表日期：2023
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Selective and stable base pairing by alkynylated nucleosides featuring a spatially-separated recognition interface

具有空间分离识别界面的炔基化核苷的选择性和稳定碱基配对

期刊:Nucleic Acids Research
影响因子:16.6
doi:10.1093/nar/gkac140
Hidenori Okamura, Giang Hoang Trinh, Zhuoxin Dong, Yoshiaki Masaki, Kohji Seio, Fumi Nagatsugi
信号转导
发表日期：2022
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Quantification of synthetic errors during chemical synthesis of DNA and its suppression by non-canonical nucleosides

DNA 化学合成过程中合成误差的量化及其通过非典型核苷的抑制

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-022-16222-2
Yoshiaki Masaki, Yukiko Onishi, Kohji Seio
信号转导
发表日期：2022
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Novel EGFP reporter cell and mouse models for sensitive imaging and quantification of exon skipping

用于外显子跳跃灵敏成像和定量分析的新型EGFP报告细胞和小鼠模型

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-020-67077-4.
Yuko Hara,Yoshitaka Mizobe,Yukiko U Inoue,Yasumasa Hashimoto,Norio Motohashi,Yoshiaki Masaki,Kohji Seio,Shin'ichi Takeda,Tetsuya Nagata,Matthew J A Wood,Takayoshi Inoue,Yoshitsugu Aoki
Mouse
细胞生物学
EGF
GFP
发表日期：2020
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Application of 2'-O-(2-N-Methylcarbamoylethyl) Nucleotides in RNase H-Dependent Antisense Oligonucleotides

2'-O-(2-N-甲基氨基甲酰乙基)核苷酸在RNase H依赖性反义寡核苷酸中的应用

期刊:Nucleic Acid Therapeutics
影响因子:4.7
doi:10.1089/nat.2018.0738
Masaki, Yoshiaki; Iriyama, Yusuke; Nakajima, Hiroyuki; Kuroda, Yusuke; Kanaki, Tatsuro; Furukawa, Satoshi; Sekine, Mitsuo; Seio, Kohji
发表日期：2018
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Synthesis and triplex-forming properties of oligonucleotides capable of recognizing corresponding DNA duplexes containing four base pairs

合成能够识别含有四个碱基对的相应DNA双链的寡核苷酸及其三链体形成特性

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkv496
Ohkubo, Akihiro; Yamada, Kenji; Ito, Yu; Yoshimura, Kiichi; Miyauchi, Koichiro; Kanamori, Takashi; Masaki, Yoshiaki; Seio, Kohji; Yuasa, Hideya; Sekine, Mitsuo
发表日期：2015
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Chemical synthesis of U1 snRNA derivatives

U1 snRNA衍生物的化学合成

期刊:Organic Letters
影响因子:5
doi:10.1021/ol401917r
Ohkubo, Akihiro; Kondo, Yasushi; Suzuki, Makoto; Kobayashi, Haruki; Kanamori, Takashi; Masaki, Yoshiaki; Seio, Kohji; Nagai, Kiyoshi; Sekine, Mitsuo
发表日期：2013
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