日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Gene expression of tight junctions in foreskin is not affected by HIV pre-exposure prophylaxis

包皮紧密连接的基因表达不受艾滋病毒暴露前预防的影响

Emily L Webb, Stefan Petkov, Heejin Yun, Laura Else, Limakatso Lebina, Jennifer Serwanga, Azure-Dee A P Pillay, Thabiso B Seiphetlo, Susan Mugaba, Patricia Namubiru, Geoffrey Odoch, Daniel Opoka, Andrew S Ssemata, Pontiano Kaleebu, Saye Khoo, Neil Martinson, Julie Fox, Clive M Gray, Carolina Herrera

Dose finding study for on-demand HIV pre-exposure prophylaxis for insertive sex in sub-Saharan Africa: results from the CHAPS open label randomised controlled trial

撒哈拉以南非洲地区针对插入性行为的 HIV 暴露前预防按需用药剂量探索研究:来自 CHAPS 开放标签随机对照试验的结果

Carolina Herrera, Jennifer Serwanga, Laura Else, Lebina Limakatso, Daniel Opoka, Andrew S Ssemata, Azure-Dee Pillay, Patricia Namubiru, Thabiso B Seiphetlo, Geoffrey Odoch, Susan Mugaba, Portia Seatlholo, Amara Alieu, Sujan Dilly Penchala, Richard Muhumuza, Berenice Alinde, Stefan Petkov, Kyle O'Hag

Bacterial microbiome and host inflammatory gene expression in foreskin tissue.

包皮组织中的细菌微生物群和宿主炎症基因表达

Maust Brandon S, Petkov Stefan, Herrera Carolina, Feng Colin, Brown Bryan P, Lebina Limakatso, Opoka Daniel, Ssemata Andrew, Pillay Natasha, Serwanga Jennifer, Seatlholo Portia, Namubiru Patricia, Odoch Geoffrey, Mugaba Susan, Seiphetlo Thabiso, Gray Clive M, Kaleebu Pontiano, Webb Emily L, Martinson Neil, Chiodi Francesca, Fox Julie, Jaspan Heather B

Proteomic Analysis of Mucosal and Systemic Responses to SARS-CoV-2 Antigen

SARS-CoV-2抗原黏膜和全身反应的蛋白质组学分析

Martinson, Neil; Gordhan, Bhavna; Petkov, Stefan; Pillay, Azure-Dee; Seiphetlo, Thabiso; Singh, Natasha; Otwombe, Kennedy; Lebina, Limakatso; Fredolini, Claudia; Chiodi, Francesca; Fox, Julie; Kana, Bavesh; Herrera, Carolina

A randomized clinical trial of on-demand oral pre-exposure prophylaxis does not modulate lymphoid/myeloid HIV target cell density in the foreskin

一项随机临床试验表明,按需口服暴露前预防药物不会调节包皮中淋巴/髓系 HIV 靶细胞的密度。

Rametse, Cosnet L; Webb, Emily L; Herrera, Carolina; Alinde, Berenice; Besethi, Asiphe; Motaung, Bongani; Mbangiwa, Tshepiso; Leach, Lloyd; Sebaa, Shorok; Pillay, Azure-Dee A P; Seiphetlo, Thabiso B; Malhangu, Boitshoko; Petkov, Stefan; Else, Laura; Mugaba, Susan; Namubiru, Patricia; Odoch, Geoffrey; Opoka, Daniel; Serwanga, Jennifer; Ssemata, Andrew S; Kaleebu, Pontiano; Khoo, Saye; Lebina, Limakatso; Martinson, Neil; Chiodi, Francesca; Fox, Julie; Gray, Clive M

Evaluation of a human mucosal tissue explant model for SARS-CoV-2 replication

评估人黏膜组织外植体模型对SARS-CoV-2复制的影响

Gordhan, Bhavna Gowan; Herrera, Carolina; Pillay, Azure-Dee; Seiphetlo, Thabiso; Ealand, Christopher Shawn; Machowski, Edith; Singh, Natasha; Seatholo, Ntombexolo; Otwombe, Kennedy; Lebina, Limakatso; Frise, Rebecca; Scarlatti, Gabriella; Chiodi, Francesca; Martinson, Neil; Fox, Julie; Kana, Bavesh Davandra

SMA-TB: study protocol for the phase 2b randomized double-blind, placebo-controlled trial to estimate the potential efficacy and safety of two repurposed drugs, acetylsalicylic acid and ibuprofen, for use as adjunct therapy added to, and compared with, the standard WHO recommended TB regimen

SMA-TB:一项2b期随机双盲安慰剂对照试验的研究方案,旨在评估两种重新利用的药物——乙酰水杨酸和布洛芬——作为辅助疗法添加到世界卫生组织推荐的标准结核病治疗方案中并与之进行比较的潜在疗效和安全性。

Arias, Lilibeth; Otwombe, Kennedy; Waja, Ziyaad; Tukvadze, Nestani; Korinteli, Tamta; Moloantoa, Tumelo; Fonseca, Kaori L; Pillay, Natasha; Seiphetlo, Thabiso; Ouchi-Vernet, Dan; Siles, Adrian; Carabias, Lidia; Quiñones, Carles; Vashakidze, Sergo; Martinson, Neil; Vilaplana, Cristina

Short-term oral pre-exposure prophylaxis against HIV-1 modulates the transcriptome of foreskin tissue in young men in Africa

短期口服HIV-1暴露前预防药物可调节非洲年轻男性包皮组织的转录组

Petkov, Stefan; Herrera, Carolina; Else, Laura; Lebina, Limakatso; Opoka, Daniel; Seiphetlo, Thabiso B; Pillay, Azure-Dee Ap; Mugaba, Susan; Namubiru, Patricia; Odoch, Geoffrey; Ssemata, Andrew S; Serwanga, Jennifer; Kaleebu, Pontiano; Webb, Emily L; Khoo, Saye; Martinson, Neil; Gray, Clive M; Fox, Julie; Chiodi, Francesca

Mobilization of systemic CCL4 following HIV pre-exposure prophylaxis in young men in Africa

非洲青年男性接受 HIV 暴露前预防后全身 CCL4 的动员

Petkov, Stefan; Herrera, Carolina; Else, Laura; Mugaba, Susan; Namubiru, Patricia; Odoch, Geoffrey; Opoka, Daniel; Pillay, Azure-Dee A P; Seiphetlo, Thabiso B; Serwanga, Jennifer; Ssemata, Andrew S; Kaleebu, Pontiano; Webb, Emily L; Khoo, Saye; Lebina, Limakatso; Gray, Clive M; Martinson, Neil; Fox, Julie; Chiodi, Francesca

Pre-Clinical Evaluation of Tenofovir and Tenofovir Alafenamide for HIV-1 Pre-Exposure Prophylaxis in Foreskin Tissue

替诺福韦和替诺福韦艾拉酚胺用于包皮组织 HIV-1 暴露前预防的临床前评估

Laura Else, Sujan D Penchala, Azure-Dee Pillay, Thabiso B Seiphetlo, Limakatso Lebina, Christian Callebaut, Suks Minhas, Roland Morley, Tina Rashid, Neil Martinson, Julie Fox, Saye Khoo, Carolina Herrera; CHAPS Consortium