Sekler Israel相关文献与解析，生知库 | 链接生命科学的每一步

Mitochondrial dysfunction mediated by ER-calcium dysregulation in neurons derived from Alzheimer's disease patients.

阿尔茨海默病患者神经元中内质网钙失调介导的线粒体功能障碍

doi:10.1186/s40478-025-02023-x

Mustaly-Kalimi Sarah, Gallegos Wacey, Steinbrenner Daniel, Gupta Smriti, Houcek Aiden J, Bennett David A, Marr Robert A, Peterson Daniel A, Sekler Israel, Stutzmann Grace E

Loss of the zinc receptor ZnR/GPR39 in mice enhances anxiety-related behavior and motor deficits, and modulates KCC2 expression in the amygdala

小鼠锌受体ZnR/GPR39的缺失会加剧焦虑相关行为和运动障碍，并调节杏仁核中KCC2的表达。

期刊:Behavioral and Brain Functions

影响因子:3.3

doi:10.1186/s12993-024-00254-x

Sagi, Romi; Chakraborty, Moumita; Bogdanovic, Milos; Asraf, Hila; Sekler, Israel; Kofman, Ora; Cohen, Hagit; Hershfinkel, Michal

Preserving and enhancing mitochondrial function after stroke to protect and repair the neurovascular unit: novel opportunities for nanoparticle-based drug delivery

中风后维持和增强线粒体功能以保护和修复神经血管单元：基于纳米颗粒的药物递送的新机遇

期刊:Frontiers in Cellular Neuroscience

影响因子:4

doi:10.3389/fncel.2023.1226630

Novorolsky, Robyn J; Kasheke, Gracious D S; Hakim, Antoine; Foldvari, Marianna; Dorighello, Gabriel G; Sekler, Israel; Vuligonda, Vidyasagar; Sanders, Martin E; Renden, Robert B; Wilson, Justin J; Robertson, George S

Protein mishandling and impaired lysosomal proteolysis generated through calcium dysregulation in Alzheimer's disease

阿尔茨海默病中钙失调导致的蛋白质处理异常和溶酶体蛋白水解受损

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2211999119

Mustaly-Kalimi, Sarah; Gallegos, Wacey; Marr, Robert A; Gilman-Sachs, Alice; Peterson, Daniel A; Sekler, Israel; Stutzmann, Grace E

阿尔茨海默症

发表日期：2022

文献求助收藏

Frequency- and spike-timing-dependent mitochondrial Ca(2+) signaling regulates the metabolic rate and synaptic efficacy in cortical neurons

频率和脉冲时间依赖性的线粒体Ca(2+)信号传导调节皮层神经元的代谢率和突触效能

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.74606

Stoler, Ohad; Stavsky, Alexandra; Khrapunsky, Yana; Melamed, Israel; Stutzmann, Grace; Gitler, Daniel; Sekler, Israel; Fleidervish, Ilya

Author Correction: Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation

作者更正：线粒体NCLX的异常活性与突触传递受损有关，并与智力低下相关。

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-021-02312-w

Stavsky, Alexandra; Stoler, Ohad; Kostic, Marko; Katoshevsky, Tomer; Assali, Essam A; Savic, Ivana; Amitai, Yael; Prokisch, Holger; Leiz, Steffen; Daumer-Haas, Cornelia; Fleidervish, Ilya; Perocchi, Fabiana; Gitler, Daniel; Sekler, Israel

Elucidating the H(+) Coupled Zn(2+) Transport Mechanism of ZIP4; Implications in Acrodermatitis Enteropathica

阐明ZIP4的H(+)偶联Zn(2+)转运机制；其在肠病性肢端皮炎中的意义

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms21030734

Hoch, Eitan; Levy, Moshe; Hershfinkel, Michal; Sekler, Israel

发表日期：2020

文献求助收藏

LRRK2 deficiency induced mitochondrial Ca(2+) efflux inhibition can be rescued by Na(+)/Ca(2+)/Li(+) exchanger upregulation

LRRK2 缺陷引起的线粒体 Ca(2+) 外流抑制可通过 Na(+)/Ca(2+)/Li(+) 交换器上调来挽救。

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-019-1469-5

Ludtmann, Marthe H R; Kostic, Marko; Horne, Amy; Gandhi, Sonia; Sekler, Israel; Abramov, Andrey Y

Crosslink between calcium and sodium signalling

钙钠信号传导之间的交联

期刊:Experimental Physiology

影响因子:2.8

doi:10.1113/EP086534

Verkhratsky, Alexei; Trebak, Mohamed; Perocchi, Fabiana; Khananshvili, Daniel; Sekler, Israel

信号转导

发表日期：2018

文献求助收藏

ZIP-ZnT1 complexes mediate a local Zn(2+)-cycle regulating neuronal ZnÂ²âº transport.

ZIP-ZnT1 复合物介导局部 Zn(2+) 循环，调节神经元 ZnÂ²â 运输。

Mitochondrial dysfunction mediated by ER-calcium dysregulation in neurons derived from Alzheimer's disease patients.

阿尔茨海默病患者神经元中内质网钙失调介导的线粒体功能障碍

Loss of the zinc receptor ZnR/GPR39 in mice enhances anxiety-related behavior and motor deficits, and modulates KCC2 expression in the amygdala

小鼠锌受体ZnR/GPR39的缺失会加剧焦虑相关行为和运动障碍，并调节杏仁核中KCC2的表达。

Preserving and enhancing mitochondrial function after stroke to protect and repair the neurovascular unit: novel opportunities for nanoparticle-based drug delivery

中风后维持和增强线粒体功能以保护和修复神经血管单元：基于纳米颗粒的药物递送的新机遇

Protein mishandling and impaired lysosomal proteolysis generated through calcium dysregulation in Alzheimer's disease

阿尔茨海默病中钙失调导致的蛋白质处理异常和溶酶体蛋白水解受损

Frequency- and spike-timing-dependent mitochondrial Ca(2+) signaling regulates the metabolic rate and synaptic efficacy in cortical neurons

频率和脉冲时间依赖性的线粒体Ca(2+)信号传导调节皮层神经元的代谢率和突触效能

Author Correction: Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation

作者更正：线粒体NCLX的异常活性与突触传递受损有关，并与智力低下相关。

Elucidating the H(+) Coupled Zn(2+) Transport Mechanism of ZIP4; Implications in Acrodermatitis Enteropathica

阐明ZIP4的H(+)偶联Zn(2+)转运机制；其在肠病性肢端皮炎中的意义

LRRK2 deficiency induced mitochondrial Ca(2+) efflux inhibition can be rescued by Na(+)/Ca(2+)/Li(+) exchanger upregulation

LRRK2 缺陷引起的线粒体 Ca(2+) 外流抑制可通过 Na(+)/Ca(2+)/Li(+) 交换器上调来挽救。

Crosslink between calcium and sodium signalling

钙钠信号传导之间的交联

ZIP-ZnT1 complexes mediate a local Zn(2+)-cycle regulating neuronal ZnÂ²âº transport.

ZIP-ZnT1 复合物介导局部 Zn(2+) 循环，调节神经元 ZnÂ²â 运输。

Mitochondrial dysfunction mediated by ER-calcium dysregulation in neurons derived from Alzheimer's disease patients.

阿尔茨海默病患者神经元中内质网钙失调介导的线粒体功能障碍

Loss of the zinc receptor ZnR/GPR39 in mice enhances anxiety-related behavior and motor deficits, and modulates KCC2 expression in the amygdala

小鼠锌受体ZnR/GPR39的缺失会加剧焦虑相关行为和运动障碍，并调节杏仁核中KCC2的表达。

Preserving and enhancing mitochondrial function after stroke to protect and repair the neurovascular unit: novel opportunities for nanoparticle-based drug delivery

中风后维持和增强线粒体功能以保护和修复神经血管单元：基于纳米颗粒的药物递送的新机遇

Protein mishandling and impaired lysosomal proteolysis generated through calcium dysregulation in Alzheimer's disease

阿尔茨海默病中钙失调导致的蛋白质处理异常和溶酶体蛋白水解受损

Frequency- and spike-timing-dependent mitochondrial Ca(2+) signaling regulates the metabolic rate and synaptic efficacy in cortical neurons

频率和脉冲时间依赖性的线粒体Ca(2+)信号传导调节皮层神经元的代谢率和突触效能

Author Correction: Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation

作者更正：线粒体NCLX的异常活性与突触传递受损有关，并与智力低下相关。

Elucidating the H(+) Coupled Zn(2+) Transport Mechanism of ZIP4; Implications in Acrodermatitis Enteropathica

阐明ZIP4的H(+)偶联Zn(2+)转运机制；其在肠病性肢端皮炎中的意义

LRRK2 deficiency induced mitochondrial Ca(2+) efflux inhibition can be rescued by Na(+)/Ca(2+)/Li(+) exchanger upregulation

LRRK2 缺陷引起的线粒体 Ca(2+) 外流抑制可通过 Na(+)/Ca(2+)/Li(+) 交换器上调来挽救。

Crosslink between calcium and sodium signalling

钙钠信号传导之间的交联

ZIP-ZnT1 complexes mediate a local Zn(2+)-cycle regulating neuronal ZnÂ²âº transport.