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Time-dependent recruitment of GAF, ISGF3 and IRF1 complexes shapes IFNα and IFNγ-activated transcriptional responses and explains mechanistic and functional overlap

GAF、ISGF3 和 IRF1 复合物的时间依赖性募集塑造了 IFNα 和 IFNγ 激活的转录反应，并解释了机制和功能重叠

Agata Sekrecka, Katarzyna Kluzek, Michal Sekrecki, Mahdi Eskandarian Boroujeni, Sanaz Hassani, Shota Yamauchi, Kiyonao Sada, Joanna Wesoly, Hans A R Bluyssen

信号转导

发表日期：2023

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Dysregulated Interferon Response and Immune Hyperactivation in Severe COVID-19: Targeting STATs as a Novel Therapeutic Strategy

重症 COVID-19 中干扰素反应失调和免疫过度激活：靶向 STAT 作为一种新型治疗策略

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2022.888897

Eskandarian Boroujeni, Mahdi; Sekrecka, Agata; Antonczyk, Aleksandra; Hassani, Sanaz; Sekrecki, Michal; Nowicka, Hanna; Lopacinska, Natalia; Olya, Arta; Kluzek, Katarzyna; Wesoly, Joanna; Bluyssen, Hans A R

Distribution of alternative untranslated regions within the mRNA of the CELF1 splicing factor affects its expression

CELF1剪接因子mRNA中不同非翻译区的分布会影响其表达。

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-021-03901-9

Arkadiusz Kajdasz,Daria Niewiadomska,Michal Sekrecki,Krzysztof Sobczak

Short antisense oligonucleotides alleviate the pleiotropic toxicity of RNA harboring expanded CGG repeats

短反义寡核苷酸可减轻含有扩增 CGG 重复序列的 RNA 的多效性毒性

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-021-21021-w

Magdalena Derbis, Emre Kul, Daria Niewiadomska, Michał Sekrecki, Agnieszka Piasecka, Katarzyna Taylor, Renate K Hukema, Oliver Stork, Krzysztof Sobczak

MEF2C shapes the microtranscriptome during differentiation of skeletal muscles

MEF2C 在骨骼肌分化过程中塑造微转录组

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-021-82706-2

Agnieszka Piasecka, Michał Sekrecki, Michał Wojciech Szcześniak, Krzysztof Sobczak

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发表日期：2021

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Quantitative Evaluation of Toxic Polyglycine Biosynthesis and Aggregation in Cell Models Expressing Expanded CGG Repeats

表达扩增 CGG 重复序列的细胞模型中毒性聚甘氨酸生物合成和聚集的定量评估

期刊:Frontiers in Genetics

影响因子:2.8

doi:10.3389/fgene.2018.00216

Magdalena Derbis, Patryk Konieczny, Agnieszka Walczak, Michal Sekrecki, Krzysztof Sobczak

MBNL splicing factors regulate the microtranscriptome of skeletal muscles

MBNL剪接因子调控骨骼肌的微转录组

Time-dependent recruitment of GAF, ISGF3 and IRF1 complexes shapes IFNα and IFNγ-activated transcriptional responses and explains mechanistic and functional overlap

GAF、ISGF3 和 IRF1 复合物的时间依赖性募集塑造了 IFNα 和 IFNγ 激活的转录反应，并解释了机制和功能重叠

Dysregulated Interferon Response and Immune Hyperactivation in Severe COVID-19: Targeting STATs as a Novel Therapeutic Strategy

重症 COVID-19 中干扰素反应失调和免疫过度激活：靶向 STAT 作为一种新型治疗策略

Distribution of alternative untranslated regions within the mRNA of the CELF1 splicing factor affects its expression

CELF1剪接因子mRNA中不同非翻译区的分布会影响其表达。

Short antisense oligonucleotides alleviate the pleiotropic toxicity of RNA harboring expanded CGG repeats

短反义寡核苷酸可减轻含有扩增 CGG 重复序列的 RNA 的多效性毒性

MEF2C shapes the microtranscriptome during differentiation of skeletal muscles

MEF2C 在骨骼肌分化过程中塑造微转录组

Quantitative Evaluation of Toxic Polyglycine Biosynthesis and Aggregation in Cell Models Expressing Expanded CGG Repeats

表达扩增 CGG 重复序列的细胞模型中毒性聚甘氨酸生物合成和聚集的定量评估