日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Doxycycline decreases amyloidogenic light chain-induced autophagy in isolated primary cardiac myocytes

强力霉素可降低分离的原代心肌细胞中淀粉样蛋白轻链诱导的自噬

Valero-Muñoz, María; Wilson, Richard M; Bretón-Romero, Rosa; Croteau, Dominique; Seldin, David C; Sam, Flora

CK2 inhibitor CX-4945 destabilizes NOTCH1 and synergizes with JQ1 against human T-acute lymphoblastic leukemic cells

CK2抑制剂CX-4945可使NOTCH1不稳定,并与JQ1协同作用对抗人T细胞急性淋巴细胞白血病细胞。

Lian, Haiwei; Li, Dun; Zhou, Yun; Landesman-Bollag, Esther; Zhang, Guanglan; Anderson, Nicole M; Tang, Kevin Charles; Roderick, Justine E; Kelliher, Michelle A; Seldin, David C; Fu, Hui; Feng, Hui

Heart Failure Resulting From Age-Related Cardiac Amyloid Disease Associated With Wild-Type Transthyretin: A Prospective, Observational Cohort Study

与野生型转甲状腺素蛋白相关的年龄相关性心脏淀粉样变性导致的心力衰竭:一项前瞻性观察队列研究

Connors, Lawreen H; Sam, Flora; Skinner, Martha; Salinaro, Francesco; Sun, Fangui; Ruberg, Frederick L; Berk, John L; Seldin, David C

Risk factors for venous thromboembolism in immunoglobulin light chain amyloidosis

免疫球蛋白轻链淀粉样变性患者发生静脉血栓栓塞的危险因素

Bever, Katherine M; Masha, Luke I; Sun, Fangui; Stern, Lauren; Havasi, Andrea; Berk, John L; Sanchorawala, Vaishali; Seldin, David C; Sloan, J Mark

Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity

溶酶体功能障碍和自噬受损是淀粉样蛋白轻链介导的心脏毒性的发病机制基础。

Guan, Jian; Mishra, Shikha; Qiu, Yiling; Shi, Jianru; Trudeau, Kyle; Las, Guy; Liesa, Marc; Shirihai, Orian S; Connors, Lawreen H; Seldin, David C; Falk, Rodney H; MacRae, Calum A; Liao, Ronglih

Repurposing diflunisal for familial amyloid polyneuropathy: a randomized clinical trial

二氟尼柳用于治疗家族性淀粉样多发性神经病:一项随机临床试验

Berk, John L; Suhr, Ole B; Obici, Laura; Sekijima, Yoshiki; Zeldenrust, Steven R; Yamashita, Taro; Heneghan, Michael A; Gorevic, Peter D; Litchy, William J; Wiesman, Janice F; Nordh, Erik; Corato, Manuel; Lozza, Alessandro; Cortese, Andrea; Robinson-Papp, Jessica; Colton, Theodore; Rybin, Denis V; Bisbee, Alice B; Ando, Yukio; Ikeda, Shu-ichi; Seldin, David C; Merlini, Giampaolo; Skinner, Martha; Kelly, Jeffery W; Dyck, Peter J

Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity.

Stanniocalcin1 是淀粉样变性轻链诱导心脏毒性的关键介质

Guan Jian, Mishra Shikha, Shi Jianru, Plovie Eva, Qiu Yiling, Cao Xin, Gianni Davide, Jiang Bingbing, Del Monte Federica, Connors Lawreen H, Seldin David C, Lavatelli Francesca, Rognoni Paola, Palladini Giovanni, Merlini Giampaolo, Falk Rodney H, Semigran Marc J, Dec G William Jr, Macrae Calum A, Liao Ronglih

Amyloidosis of the gastrointestinal tract: a 13-year, single-center, referral experience

胃肠道淀粉样变性:一项为期13年的单中心转诊经验

Cowan, Andrew J; Skinner, Martha; Seldin, David C; Berk, John L; Lichtenstein, David R; O'Hara, Carl J; Doros, Gheorghe; Sanchorawala, Vaishali

Melphalan, lenalidomide and dexamethasone for the treatment of immunoglobulin light chain amyloidosis: results of a phase II trial

美法仑、来那度胺和地塞米松治疗免疫球蛋白轻链淀粉样变性:一项 II 期试验的结果

Sanchorawala, Vaishali; Patel, Jaymin M; Sloan, J Mark; Shelton, Anthony C; Zeldis, Jerome B; Seldin, David C

Circulating matrix metalloproteinases and tissue inhibitors of metalloproteinases in cardiac amyloidosis.

心脏淀粉样变性中的循环基质金属蛋白酶和金属蛋白酶组织抑制剂

Tanaka Komei, Essick Eric E, Doros Gheorghe, Tanriverdi Kahraman, Connors Lawreen H, Seldin David C, Sam Flora