日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Morphological map of under- and overexpression of genes in human cells

人类细胞中基因表达不足和过表达的形态学图谱

Chandrasekaran, Srinivas Niranj; Alix, Eric; Arevalo, John; Borowa, Adriana; Byrne, Patrick J; Charles, William G; Chen, Zitong S; Cimini, Beth A; Deng, Boxiong; Doench, John G; Ewald, Jessica D; Fritchman, Briana; Fuller, Colin J; Gaetz, Jedidiah; Goodale, Amy; Haghighi, Marzieh; Han, Yu; Hanifehlou, Zahra; Hennig, Holger; Hernandez, Desiree; Jacob, Christina B; James, Tim; Jetka, Tomasz; Kalinin, Alexandr A; Komalo, Ben; Kost-Alimova, Maria; Krawiec, Tomasz; Marion, Brittany A; Martin, Glynn; McCarthy, Nicola Jane; Miller, Lisa; Monsees, Arne; Moshkov, Nikita; Muñoz, Alán F; Ogier, Arnaud; Otrocka, Magdalena; Rataj, Krzysztof; Root, David E; Rubbo, Francesco; Scrace, Simon; Selinger, Douglas W; Senft, Rebecca A; Sommer, Peter; Thibaudeau, Amandine; Trisorus, Sarah; Valiya Veettil, Rahul; Van Trump, William J; Wang, Sui; Warchoł, Michał; Weisbart, Erin; Weiss, Amélie; Wiest, Michael; Zaremba, Agata; Zinovyev, Andrei; Singh, Shantanu; Carpenter, Anne E

Phenotypic Screening Coupled with AI-Driven Target Deconvolution Identifies α-Terthienyl as a Dual DPP-IV/HSD17β13 Modulator with Efficacy in a Mouse Model of MASLD

表型筛选结合人工智能驱动的靶点解卷积,鉴定出α-三噻吩是一种双重DPP-IV/HSD17β13调节剂,在MASLD小鼠模型中具有疗效。

Hoegeman, Kathryn M; Wotring, Jesse W; Fursmidt, Reid; Gaetz, Jedidiah; Khalil, Ehab M; Selinger, Douglas W; Kovalenko, Ilya; Schultz, Tracey L; McCarty, Sean M; O'Meara, Matthew J; Clasby, Martin C; Sexton, Jonathan Z

Global RNA half-life analysis in Escherichia coli reveals positional patterns of transcript degradation.

大肠杆菌中 RNA 半衰期的全局分析揭示了转录本降解的位置模式

Selinger Douglas W, Saxena Rini Mukherjee, Cheung Kevin J, Church George M, Rosenow Carsten