日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An exonuclease-resistant chain-terminating nucleotide analogue targeting the SARS-CoV-2 replicase complex

一种靶向SARS-CoV-2复制酶复合物的抗核酸外切酶链终止核苷酸类似物

Shannon, Ashleigh; Chazot, Aurélie; Feracci, Mikael; Falcou, Camille; Fattorini, Véronique; Selisko, Barbara; Good, Steven; Moussa, Adel; Sommadossi, Jean-Pierre; Ferron, François; Alvarez, Karine; Canard, Bruno

Inhibition of Arenaviridae nucleoprotein exonuclease by bisphosphonate

双膦酸盐对沙粒病毒核蛋白外切酶的抑制作用

Nguyen, Thi Hong Van; Yekwa, Elsie; Selisko, Barbara; Canard, Bruno; Alvarez, Karine; Ferron, François

Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis

法匹拉韦被快速且易被病毒RNA聚合酶复合物吸收后,会导致SARS-CoV-2致命突变。

Ashleigh Shannon,Barbara Selisko,Nhung-Thi-Tuyet Le,Johanna Huchting,Franck Touret,Géraldine Piorkowski,Véronique Fattorini,François Ferron,Etienne Decroly,Chris Meier,Bruno Coutard,Olve Peersen,Bruno Canard

Antiviral activity of the natural alkaloid anisomycin against dengue and Zika viruses

天然生物碱茴香霉素对登革热和寨卡病毒的抗病毒活性

V M Quintana, B Selisko, J E Brunetti, C Eydoux, J C Guillemot, B Canard, E B Damonte, J G Julander, V Castilla

Synthesis and biological evaluation of novel flexible nucleoside analogues that inhibit flavivirus replication in vitro

合成并生物学评价新型柔性核苷类似物在体外抑制黄病毒复制的活性

Thames, Joy E; Waters, Charles D 3rd; Valle, Coralie; Bassetto, Marcella; Aouadi, Wahiba; Martin, Baptiste; Selisko, Barbara; Falat, Arissa; Coutard, Bruno; Brancale, Andrea; Canard, Bruno; Decroly, Etienne; Seley-Radtke, Katherine L

Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase

法匹拉韦直击SARS-CoV-2的阿喀琉斯之踵——RNA聚合酶。

Shannon, A; Selisko, B; Le, Ntt; Huchting, J; Touret, F; Piorkowski, G; Fattorini, V; Ferron, F; Decroly, E; Meier, C; Coutard, B; Peersen, O; Canard, B

Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases

黄病毒RNA依赖性RNA聚合酶核苷酸选择保真度的结构和功能基础

Selisko, Barbara; Papageorgiou, Nicolas; Ferron, François; Canard, Bruno

Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives

寨卡病毒甲基转移酶:结构与功能及其在药物设计中的应用前景

Coutard, Bruno; Barral, Karine; Lichière, Julie; Selisko, Barbara; Martin, Baptiste; Aouadi, Wahiba; Lombardia, Miguel Ortiz; Debart, Françoise; Vasseur, Jean-Jacques; Guillemot, Jean Claude; Canard, Bruno; Decroly, Etienne

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family

RNA依赖性RNA聚合酶的RNA模板通道可作为开发针对病毒家族内多个属病毒的抗病毒疗法的靶点

van der Linden, Lonneke; Vives-Adrián, Laia; Selisko, Barbara; Ferrer-Orta, Cristina; Liu, Xinran; Lanke, Kjerstin; Ulferts, Rachel; De Palma, Armando M; Tanchis, Federica; Goris, Nesya; Lefebvre, David; De Clercq, Kris; Leyssen, Pieter; Lacroix, Céline; Pürstinger, Gerhard; Coutard, Bruno; Canard, Bruno; Boehr, David D; Arnold, Jamie J; Cameron, Craig E; Verdaguer, Nuria; Neyts, Johan; van Kuppeveld, Frank J M

The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain

登革病毒蛋白NS5的甲基转移酶结构域确保聚合酶结构域能够高效地启动和延伸RNA合成。

Potisopon, Supanee; Priet, Stéphane; Collet, Axelle; Decroly, Etienne; Canard, Bruno; Selisko, Barbara