日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanisms of clinical resistance to selective FGFR2 inhibition by lirafugratinib.

利拉夫替尼选择性抑制FGFR2的临床耐药机制。

Ellis H, Balasooriya E R, Varkaris A, Hajian B, Wan J, Shekhar M, Gritti I, Vijay V, Albertelli L, Piot S, Lau K, Kehlmann A, Chevalier N, Nugent F W, Zhen Y, Silveira V S, Sellers W R, Corcoran R B, Juric D, Bardeesy N

TERT promoter mutations and monoallelic activation of TERT in cancer

TERT启动子突变和TERT单等位基因激活在癌症中的作用

Huang, F W; Bielski, C M; Rinne, M L; Hahn, W C; Sellers, W R; Stegmeier, F; Garraway, L A; Kryukov, G V

Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation

子宫内膜癌的整合基因组分析表明,侵袭性肿瘤与PI3激酶激活指标相关。

Salvesen, H B; Carter, S L; Mannelqvist, M; Dutt, A; Getz, G; Stefansson, I M; Raeder, M B; Sos, M L; Engelsen, I B; Trovik, J; Wik, E; Greulich, H; Bø, T H; Jonassen, I; Thomas, R K; Zander, T; Garraway, L A; Oyan, A M; Sellers, W R; Kalland, K H; Meyerson, M; Akslen, L A; Beroukhim, R

Phosphorylation of the PTEN tail regulates protein stability and function

PTEN尾部的磷酸化调节蛋白质的稳定性和功能

Vazquez, F; Ramaswamy, S; Nakamura, N; Sellers, W R

Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle

细胞在退出细胞周期时会降解一种具有E1A样特性的新型分化抑制因子。

Miyake, S; Sellers, W R; Safran, M; Li, X; Zhao, W; Grossman, S R; Gan, J; DeCaprio, J A; Adams, P D; Kaelin, W G Jr

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

叉头转录因子是 PTEN 下游细胞死亡和细胞周期阻滞的关键效应因子

Nakamura N, Ramaswamy S, Vazquez F, Signoretti S, Loda M, Sellers W R

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

视网膜母细胞瘤蛋白无需与E2F稳定结合即可激活转录、促进分化和抑制肿瘤细胞生长

Sellers, W R; Novitch, B G; Miyake, S; Heith, A; Otterson, G A; Kaye, F J; Lassar, A B; Kaelin, W G Jr