日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The macrocyclic peptide rhesus theta defensin 1 activates interferon and antiviral pathways in human monocytes

大环肽恒河猴θ防御素1激活人单核细胞中的干扰素和抗病毒通路

Tongaonkar, Prasad; Trinh, Katie K; Henley, Jill E; Sell, Philip J; Thakker, Vyoma; Ouellette, André J; Selsted, Michael E

Inhibition of miR-146a Expression and Regulation of Endotoxin Tolerance by Rhesus Theta-Defensin-1.

恒河猴θ防御素-1抑制miR-146a表达并调节内毒素耐受性

Tongaonkar Prasad, Trinh Katie K, Ouellette André J, Selsted Michael E

Preclinical Pharmacokinetics and Safety of Intravenous RTD-1

静脉注射RTD-1的临床前药代动力学和安全性

Park, A Young J; Tran, Dat Q; Schaal, Justin B; Wang, Mengxi; Selsted, Michael E; Beringer, Paul M

A host-directed macrocyclic peptide therapeutic for MDR gram negative bacterial infections

一种针对多重耐药革兰氏阴性细菌感染的宿主定向大环肽治疗剂

Justin B Schaal, Yoshihiro Eriguchi, Dat Q Tran, Patti A Tran, Chase Hawes, Anthony E Cabebe, Kaitlyn Pike, Katie Trinh, André J Ouellette, Michael E Selsted

Anti-Inflammatory Effects of RTD-1 in a Murine Model of Chronic Pseudomonas aeruginosa Lung Infection: Inhibition of NF-κB, Inflammasome Gene Expression, and Pro-IL-1β Biosynthesis

RTD-1 在小鼠慢性铜绿假单胞菌肺部感染模型中的抗炎作用:抑制 NF-κB、炎症小体基因表达和 Pro-IL-1β 生物合成

Mansour A Dughbaj, Jordanna G Jayne, A Young J Park, Timothy J Bensman, Marquerita Algorri, Andre J Ouellette, Michael E Selsted, Paul M Beringer

Host Defense Peptides as Templates for Antifungal Drug Development

宿主防御肽作为抗真菌药物开发的模板

Basso, Virginia; Tran, Dat Q; Ouellette, André J; Selsted, Michael E

Rhesus Theta Defensin 1 Promotes Long Term Survival in Systemic Candidiasis by Host Directed Mechanisms

恒河猴θ防御素1通过宿主导向机制促进系统性念珠菌病中的长期存活

Basso, Virginia; Tran, Dat Q; Schaal, Justin B; Tran, Patti; Eriguchi, Yoshihiro; Ngole, Diana; Cabebe, Anthony E; Park, A Young; Beringer, Paul M; Ouellette, André J; Selsted, Michael E

RTD-1 therapeutically normalizes synovial gene signatures in rat autoimmune arthritis and suppresses proinflammatory mediators in RA synovial fibroblasts.

RTD-1 可治疗性地使大鼠自身免疫性关节炎的滑膜基因特征正常化,并抑制 RA 滑膜成纤维细胞中的促炎介质

Tongaonkar Prasad, Punj Vasu, Subramanian Akshay, Tran Dat Q, Trinh Katie K, Schaal Justin B, Laragione Teresina, Ouellette André J, Gulko Percio S, Selsted Michael E

Essential role of IFN-γ in T cell-associated intestinal inflammation

IFN-γ 在 T 细胞相关肠道炎症中的重要作用

Yoshihiro Eriguchi, Kiminori Nakamura, Yuki Yokoi, Rina Sugimoto, Shuichiro Takahashi, Daigo Hashimoto, Takanori Teshima, Tokiyoshi Ayabe, Michael E Selsted, André J Ouellette

Rhesus θ-Defensin-1 Attenuates Endotoxin-induced Acute Lung Injury by Inhibiting Proinflammatory Cytokines and Neutrophil Recruitment

恒河猴θ-防御素-1通过抑制促炎细胞因子和中性粒细胞募集减轻内毒素诱导的急性肺损伤

Jordanna G Jayne, Timothy J Bensman, Justin B Schaal, A Young J Park, Elza Kimura, Dat Tran, Michael E Selsted, Paul M Beringer