日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Therapeutic potential of PIMSR, a novel CB1 receptor neutral antagonist, for cocaine use disorder: evidence from preclinical research

新型CB1受体中性拮抗剂PIMSR治疗可卡因使用障碍的治疗潜力:来自临床前研究的证据

Galaj, Ewa; Hempel, Briana; Moore, Allamar; Klein, Benjamin; Bi, Guo-Hua; Gardner, Eliot L; Seltzman, Herbert H; Xi, Zheng-Xiong

Selective targeting of peripheral cannabinoid receptors prevents behavioral symptoms and sensitization of trigeminal neurons in mouse models of migraine and medication overuse headache

选择性靶向外周大麻素受体可预防偏头痛和药物过度使用性头痛的小鼠模型中的行为症状和三叉神经元的敏感化

Toru Yamamoto, Yatendra Mulpuri, Mikhail Izraylev, Qianyi Li, Menooa Simonian, Christian Kramme, Brian L Schmidt, Herbert H Seltzman, Igor Spigelman

α-[Amino(4-aminophenyl)thio]methylene-2-(trifluoromethyl)benzeneacetonitrile; Configurational equilibria in solution

α-[氨基(4-氨基苯基)硫代]亚甲基-2-(三氟甲基)苯乙腈;溶液中的构型平衡

McElhinny, Charles J; Lewin, Anita H; Brieaddy, Larry; Fix, Scott; Imler, Gregory H; Deschamps, Jeffrey; Mascarella, S Wayne; Seltzman, Herbert H; Anantha Reddy, P; Carroll, F Ivy

Peripherally restricted cannabinoid 1 receptor agonist as a novel analgesic in cancer-induced bone pain

外周限制性大麻素 1 受体激动剂作为癌症引起的骨痛的新型镇痛药

Hong Zhang, Dominique M Lund, Haley A Ciccone, William D Staatz, Mohab M Ibrahim, Tally M Largent-Milnes, Herbert H Seltzman, Igor Spigelman, Todd W Vanderah

Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation

合成的外周限制性大麻素通过激活CB1受体抑制化疗引起的周围神经病变疼痛症状。

Mulpuri, Yatendra; Marty, Vincent N; Munier, Joseph J; Mackie, Ken; Schmidt, Brian L; Seltzman, Herbert H; Spigelman, Igor

Synthesis and Physicochemical Characterization of the One-Carbon Carrier 10-Formyltetrahydrofolate; A Reference Standard for Metabolomics

10-甲酰四氢叶酸(一种单碳载体)的合成及理化性质表征;代谢组学参考标准

Lewin, Anita H; Silinski, Peter; Hayes, James; Gilbert, Amanda; Mascarella, S Wayne; Seltzman, Herbert H

Metabolic Profiling of CB1 Neutral Antagonists

CB1中性拮抗剂的代谢谱分析

Seltzman, Herbert H; Maitra, Rangan; Bortoff, Katharine; Henson, Jay; Reggio, Patricia H; Wesley, Daniel; Tam, Joseph

Novel Synthesis and Pharmacological Characterization of NOP Receptor Agonist 8-[(1S,3aS)-2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one (Ro 64-6198)

NOP受体激动剂8-[(1S,3aS)-2,3,3a,4,5,6-六氢-1H-菲烯-1-基]-1-苯基-1,3,8-三氮杂螺[4.5]癸烷-4-酮(Ro 64-6198)的新型合成及药理学表征

Chang, Steven D; Brieaddy, Lawrence E; Harvey, Joseph D; Lewin, Anita H; Mascarella, S Wayne; Seltzman, Herbert H; Reddy, P Anantha; Decker, Ann M; McElhinny, Charles J Jr; Zhong, Desong; Peterson, Elisha E; Navarro, Hernán A; Bruchas, Michael R; Carroll, F Ivy

Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands

利用一组新型高效GPR55选择性配体鉴定GPR55拮抗剂结合位点

Kotsikorou, Evangelia; Sharir, Haleli; Shore, Derek M; Hurst, Dow P; Lynch, Diane L; Madrigal, Karla E; Heynen-Genel, Susanne; Milan, Loribelle B; Chung, Thomas D Y; Seltzman, Herbert H; Bai, Yushi; Caron, Marc G; Barak, Larry S; Croatt, Mitchell P; Abood, Mary E; Reggio, Patricia H

Towards rational design of cannabinoid receptor 1 (CB1) antagonists for peripheral selectivity

面向外周选择性的大麻素受体1(CB1)拮抗剂的合理设计

Fulp, Alan; Bortoff, Katherine; Zhang, Yanan; Seltzman, Herbert; Snyder, Rodney; Maitra, Rangan