日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PIK3CA-related overgrowth spectrum (PROS) zebrafish models reveal pan-lineage developmental dysregulation

PIK3CA相关过度生长谱系(PROS)斑马鱼模型揭示了泛谱发育失调

Brunsdon, Hannah; Wang, Nuoya; Raredon, Micha Sam Brickman; Madsen, Ralitsa R; Semple, Robert K; Patton, E Elizabeth

Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant

免疫缺陷相关激活型PIK3R1变体的矛盾性显性负活性

Tomlinson, Patsy R; Knox, Rachel G; Perisic, Olga; Su, Helen; Brierley, Gemma V; Williams, Roger L; Semple, Robert K

Metabolic biomarkers of clinical outcomes in severe mental illness (METPSY): protocol for a prospective observational study in the Hub for metabolic psychiatry

严重精神疾病临床结局的代谢生物标志物(METPSY):代谢精神病学中心前瞻性观察研究方案

Rakshasa-Loots, Arish Mudra; Steyn, Christina; Swiffen, Duncan; Marwick, Katie F M; Semple, Robert K; Reynolds, Rebecca M; Burgess, Karl; Lawrie, Stephen M; Lightman, Stafford L; Luz, Saturnino; Smith, Daniel J

The metabolically protective energy expenditure increase of Pik3r1-related insulin resistance is not explained by Ucp1-mediated thermogenesis

Pik3r1相关胰岛素抵抗引起的代谢保护性能量消耗增加,并不能用Ucp1介导的产热作用来解释。

Luijten, Ineke; Onishi, Ami; McKay, Eleanor J; Bengtsson, Tore; Semple, Robert K

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

内分泌学会关于女性雄激素过多症评估的临床实践指南

Elhassan, Yasir S; Hawley, James M; Cussen, Leanne; Abbara, Ali; Clarke, Sophie A; Kempegowda, Punith; Dhillon-Smith, Rima K; Thadani, Puja; Busby, Maureen; Owusu-Darkwah, Lucy; Marrington, Rachel; Duncan, W Colin; Semple, Robert K; Quinton, Richard; O'Reilly, Michael W

Mesenchymal-specific Alms1 knockout in mice recapitulates metabolic features of Alström syndrome

小鼠间充质特异性 Alms1 敲除可重现 Alström 综合征的代谢特征

McKay, Eleanor J; Luijten, Ineke; Weng, Xiong; Martinez de Morentin, Pablo B; De Frutos González, Elvira; Gao, Zhanguo; Kolonin, Mikhail G; Heisler, Lora K; Semple, Robert K

GNAQ/GNA11 Mosaicism Is Associated with Abnormal Serum Calcium Indices and Microvascular Neurocalcification

GNAQ/GNA11嵌合体与血清钙指标异常和微血管神经钙化相关

Knöpfel, Nicole; Zecchin, Davide; Richardson, Hanna; Polubothu, Satyamaanasa; Barberan-Martin, Sara; Cullup, Thomas; Gholam, Karolina; Heales, Simon; Krywawych, Steve; López-Balboa, Pablo; Muwanga-Nanyonjo, Noreen; Ogunbiyi, Olumide; Puvirajasinghe, Clinda; Solman, Lea; Swarbrick, Katherine; Syed, Samira B; Tahir, Zubair; Tisdall, Martin M; Allgrove, Jeremy; Chesover, Alexander D; Aylett, Sarah E; Jacques, Thomas S; Hannan, Fadil M; Löbel, Ulrike; Semple, Robert K; Thakker, Rajesh V; Kinsler, Veronica A

UCP1 expression in human brown adipose tissue is inversely associated with cardiometabolic risk factors

人棕色脂肪组织中UCP1的表达与心血管代谢风险因素呈负相关

Kwok, T'ng Choong; Ramage, Lynne E; Kelman, Alexandra; Suchacki, Karla J; Gray, Calum; Boyle, Luke D; Semple, Scott I; MacGillivray, Tom; MacNaught, Gillian; Patel, Dilip; van Beek, Edwin J R; Semple, Robert K; Wakelin, Sonia J; Stimson, Roland H

Mitochondrial Dysfunction as a Potential Mechanism Mediating Cardiac Comorbidities in Parkinson's Disease

线粒体功能障碍可能是帕金森病心脏合并症的潜在机制

Salis Torres, Agustina; Lee, Ji-Eun; Caporali, Andrea; Semple, Robert K; Horrocks, Mathew H; MacRae, Vicky E

Female Alms1-deficient mice develop echocardiographic features of adult but not infantile Alström syndrome cardiomyopathy

雌性 Alms1 缺陷小鼠出现成人型而非婴儿型 Alström 综合征心肌病的心脏超声特征。

McKay, Eleanor J; Luijten, Ineke; Broadway-Stringer, Sophie; Thomson, Adrian; Weng, Xiong; Gehmlich, Katya; Gray, Gillian A; Semple, Robert K