日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TLR9 signaling requires ligand-induced phosphorylation of two specific tyrosine residues by EGFR and Syk.

TLR9 信号传导需要 EGFR 和 Syk 对两个特定酪氨酸残基进行配体诱导的磷酸化。

Veleeparambil Manoj, Wang Chenyao, Kessler Patricia M, Sengupta Pracheta, Das Santanu, Chakravarti Ritu, Willard Belinda, Sen Ganes C, Chattopadhyay Saurabh

The interferon-induced protein, IFIT2, requires RNA-binding activity and neuronal expression to protect mice from intranasal vesicular stomatitis virus infection

干扰素诱导蛋白IFIT2需要RNA结合活性和神经元表达才能保护小鼠免受鼻内水疱性口炎病毒感染。

Poddar, Darshana; Sharma, Nikhil; Ogino, Tomoaki; Qi, Xu; Kessler, Patricia M; Mendries, Hiran; Dutta, Ranjan; Sen, Ganes C

Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection

Ifit2缺陷会限制小鼠冠状病毒(m-CoV)中枢神经系统感染后的小胶质细胞活化和白细胞迁移。

Das Sarma, Jayasri; Burrows, Amy; Rayman, Patricia; Hwang, Mi-Hyun; Kundu, Soumya; Sharma, Nikhil; Bergmann, Cornelia; Sen, Ganes C

RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

RIG-I样受体诱导的IRF3介导的细胞凋亡通路(RIPA):一种新的抗病毒通路

Chattopadhyay, Saurabh; Sen, Ganes C

STING Requires the Adaptor TRIF to Trigger Innate Immune Responses to Microbial Infection.

STING 需要接头蛋白 TRIF 来触发对微生物感染的先天免疫反应

Wang Xin, Majumdar Tanmay, Kessler Patricia, Ozhegov Evgeny, Zhang Ying, Chattopadhyay Saurabh, Barik Sailen, Sen Ganes C

Tyrosine phosphorylation in Toll-like receptor signaling

Toll样受体信号传导中的酪氨酸磷酸化

Chattopadhyay, Saurabh; Sen, Ganes C

Sendai virus pathogenesis in mice is prevented by Ifit2 and exacerbated by interferon

Ifit2 可抑制仙台病毒在小鼠体内的致病性,而干扰素则会加剧这种致病性。

Wetzel, Jaime L; Fensterl, Volker; Sen, Ganes C

Interferon-induced protein Ifit2 protects mice from infection of the peripheral nervous system by vesicular stomatitis virus

干扰素诱导蛋白 Ifit2 可保护小鼠免受水疱性口炎病毒对周围神经系统的感染

Fensterl, Volker; Wetzel, Jaime L; Sen, Ganes C

Tissue-specific expression of transgenic secreted ACE in vasculature can restore normal kidney functions, but not blood pressure, of Ace-/- mice

在血管系统中特异性表达转基因分泌型ACE可以恢复Ace-/-小鼠的正常肾功能,但不能恢复其血压。

Chattopadhyay, Saurabh; Kessler, Sean P; Colucci, Juliana Almada; Yamashita, Michifumi; Senanayake, Preenie deS; Sen, Ganes C

p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

p53 与 DNA 甲基化和自杀性干扰素反应协同作用,维持重复序列和非编码 RNA 的表观遗传沉默。

Leonova, Katerina I; Brodsky, Leonid; Lipchick, Brittany; Pal, Mahadeb; Novototskaya, Liliya; Chenchik, Alex A; Sen, Ganes C; Komarova, Elena A; Gudkov, Andrei V