日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Assessing the Safety and Efficacy of Agonistic Monoclonal Antibody against Robo4 versus Ranibizumab in Neovascular Age-Related Macular Degeneration and Diabetic Macular Edema: A Phase I, Open-Label, Multicenter Study

评估针对 Robo4 的激动性单克隆抗体与雷珠单抗治疗新生血管性年龄相关性黄斑变性和糖尿病性黄斑水肿的安全性和有效性：一项 I 期、开放标签、多中心研究

期刊:Ophthalmology Science
影响因子:4.6
doi:10.1016/j.xops.2026.101084
Afridi, Rubbia; Senaldi, Giorgio; Hwang, Jaclyn Joyce; Nguyen, Nam; Inoue, Tatsuya; Berger, Brian; Patel, Sunil; Fazal, Zoha Zahid; Nguyen, Quan Dong; Sepah, Yasir
代谢
单克隆抗体
糖尿病
发表日期：2026
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Anti-human TLR7 antibody for therapeutic intervention in systemic lupus erythematosus

抗人TLR7抗体用于系统性红斑狼疮的治疗干预

期刊:International Immunology
影响因子:3.2
doi:10.1093/intimm/dxaf046
Fukui, Ryutaro; Murakami, Yusuke; Kanno, Atsuo; Motoi, Yuji; Manno, Atsushi; Honda, Tomohiro; Yamada, Shinnosuke; Ishiguro, Jun; Kagari, Takashi; Nakamura, Kensuke; Kadokura, Michinori; Isobe, Takashi; Tomimori, Yoshiaki; Tanaka, Jun; Senaldi, Giorgio; Shimizu, Toshiyuki; Miyake, Kensuke
红斑狼疮
TLR7
免疫/内分泌
发表日期：2026
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First-in-human study of the anti-HB-EGF antibody U3-1565 in subjects with advanced solid tumors

抗HB-EGF抗体U3-1565在晚期实体瘤患者中的首次人体研究

期刊:Investigational New Drugs
影响因子:2.7
doi:10.1007/s10637-018-0646-1
Moore, Kathleen N; Bendell, Johanna C; LoRusso, Patricia M; Olszanski, Anthony J; Zwick-Wallasch, Esther; Jansen, Mendel; Vandell, Alexander G; Senaldi, Giorgio
HB-EGF
EGF
发表日期：2019
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Phase 1 Study To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Oral Doses of DS-2969b, a Novel GyrB Inhibitor, in Healthy Subjects

一项评估新型 GyrB 抑制剂 DS-2969b 在健康受试者中多次口服给药的安全性、耐受性、药代动力学和药效学的 1 期研究

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.02537-17
Vandell, Alexander G; Inoue, Satoshi; Dennie, Justin; Nagasawa, Yasuo; Gajee, Roohi; Pav, Joe; Zhang, George; Zamora, Cynthia; Masuda, Nobuhisa; Senaldi, Giorgio
发表日期：2018
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In Vitro and In Vivo Evaluation of (89)Zr-DS-8273a as a Theranostic for Anti-Death Receptor 5 Therapy

体外和体内评价 (89)Zr-DS-8273a 作为抗死亡受体 5 疗法的诊疗一体化药物

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.16260
Burvenich, Ingrid J G; Lee, Fook-Thean; Guo, Nancy; Gan, Hui K; Rigopoulos, Angela; Parslow, Adam C; O'Keefe, Graeme J; Gong, Sylvia J; Tochon-Danguy, Henri; Rudd, Stacey E; Donnelly, Paul S; Kotsuma, Masakatsu; Ohtsuka, Toshiaki; Senaldi, Giorgio; Scott, Andrew M
信号转导
发表日期：2016
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Pulmonary inflammation induced by Pseudomonas aeruginosa lipopolysaccharide, phospholipase C, and exotoxin A: role of interferon regulatory factor 1.

铜绿假单胞菌脂多糖、磷脂酶 C 和外毒素 A 诱发的肺部炎症：干扰素调节因子 1 的作用

期刊:Infection and Immunity
影响因子:2.8
doi:10.1128/IAI.70.3.1352-1358.2002
Wieland Catharina W, Siegmund Britta, Senaldi Giorgio, Vasil Michael L, Dinarello Charles A, Fantuzzi Giamila
炎症/感染
炎症
发表日期：2002
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