日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting Mitochondrial Network Disorganization is Protective in C. elegans Models of Huntington's Disease

靶向线粒体网络紊乱对秀丽隐杆线虫亨廷顿病模型具有保护作用

Machiela, Emily; Rudich, Paige D; Traa, Annika; Anglas, Ulrich; Soo, Sonja K; Senchuk, Megan M; Van Raamsdonk, Jeremy M

Multiple genetic pathways regulating lifespan extension are neuroprotective in a G2019S LRRK2 nematode model of Parkinson's disease

在帕金森病G2019S LRRK2线虫模型中,多个调控寿命延长的基因通路具有神经保护作用。

Senchuk, Megan M; Van Raamsdonk, Jeremy M; Moore, Darren J

Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways

线粒体未折叠蛋白反应转录因子ATFS-1通过激活应激反应通路促进长寿线粒体突变体的寿命

Wu, Ziyun; Senchuk, Megan M; Dues, Dylan J; Johnson, Benjamin K; Cooper, Jason F; Lew, Leira; Machiela, Emily; Schaar, Claire E; DeJonge, Heather; Blackwell, T Keith; Van Raamsdonk, Jeremy M

Activation of DAF-16/FOXO by reactive oxygen species contributes to longevity in long-lived mitochondrial mutants in Caenorhabditis elegans

活性氧激活DAF-16/FOXO有助于秀丽隐杆线虫长寿线粒体突变体的寿命延长。

Senchuk, Megan M; Dues, Dylan J; Schaar, Claire E; Johnson, Benjamin K; Madaj, Zachary B; Bowman, Megan J; Winn, Mary E; Van Raamsdonk, Jeremy M

Uncoupling of oxidative stress resistance and lifespan in long-lived isp-1 mitochondrial mutants in Caenorhabditis elegans.

秀丽隐杆线虫长寿 isp-1 线粒体突变体中氧化应激抵抗力与寿命的脱钩

Dues Dylan J, Schaar Claire E, Johnson Benjamin K, Bowman Megan J, Winn Mary E, Senchuk Megan M, Van Raamsdonk Jeremy M

Delaying aging is neuroprotective in Parkinson's disease: a genetic analysis in C. elegans models

延缓衰老对帕金森病具有神经保护作用:秀丽隐杆线虫模型遗传分析

Cooper, Jason F; Dues, Dylan J; Spielbauer, Katie K; Machiela, Emily; Senchuk, Megan M; Van Raamsdonk, Jeremy M

Identification of new netrin family members in zebrafish: developmental expression of netrin 2 and netrin 4

斑马鱼中新netrin家族成员的鉴定:netrin 2和netrin 4的发育表达

Park, Kye Won; Urness, Lisa D; Senchuk, Megan M; Colvin, Carrie J; Wythe, Joshua D; Chien, Chi-Bin; Li, Dean Y