日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential

利用计算细胞周期分析癌细胞,筛选具有再利用潜力的FDA批准药物

Lo, Yu-Chen; Senese, Silvia; France, Bryan; Gholkar, Ankur A; Damoiseaux, Robert; Torres, Jorge Z

NMR structure-based optimization of Staphylococcus aureus sortase A pyridazinone inhibitors.

基于核磁共振结构的金黄色葡萄球菌A型分选酶哒嗪酮抑制剂的优化

Chan Albert H, Yi Sung Wook, Weiner Ethan M, Amer Brendan R, Sue Christopher K, Wereszczynski Jeff, Dillen Carly A, Senese Silvia, Torres Jorge Z, McCammon J Andrew, Miller Lloyd S, Jung Michael E, Clubb Robert T

3D Chemical Similarity Networks for Structure-Based Target Prediction and Scaffold Hopping

基于结构的靶标预测和骨架跃迁的三维化学相似性网络

Lo, Yu-Chen; Senese, Silvia; Damoiseaux, Robert; Torres, Jorge Z

Structures of potent anticancer compounds bound to tubulin

与微管蛋白结合的强效抗癌化合物的结构

McNamara, Dan E; Senese, Silvia; Yeates, Todd O; Torres, Jorge Z

Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens

用于细胞化学筛选中化合物靶标分析的大规模化学相似性网络

Lo, Yu-Chen; Senese, Silvia; Li, Chien-Ming; Hu, Qiyang; Huang, Yong; Damoiseaux, Robert; Torres, Jorge Z

Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors.

用于设计 polo-box 结构域抑制剂的动态和多药效团建模

Sakkiah Sugunadevi, Senese Silvia, Yang Qianfan, Lee Keun Woo, Torres Jorge Z

The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation

细胞周期蛋白依赖性激酶抑制剂p21是组蛋白去乙酰化酶1的关键靶点,而组蛋白去乙酰化酶1是细胞增殖的调节因子。

Zupkovitz, Gordin; Grausenburger, Reinhard; Brunmeir, Reinhard; Senese, Silvia; Tischler, Julia; Jurkin, Jennifer; Rembold, Martina; Meunier, Dominique; Egger, Gerda; Lagger, Sabine; Chiocca, Susanna; Propst, Fritz; Weitzer, Georg; Seiser, Christian

Role for histone deacetylase 1 in human tumor cell proliferation

组蛋白去乙酰化酶1在人类肿瘤细胞增殖中的作用

Senese, Silvia; Zaragoza, Katrin; Minardi, Simone; Muradore, Ivan; Ronzoni, Simona; Passafaro, Alfonso; Bernard, Loris; Draetta, Giulio F; Alcalay, Myriam; Seiser, Christian; Chiocca, Susanna