日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

2-hydroxyglutarate mediates whitening of brown adipocytes coupled to nuclear softening upon mitochondrial dysfunction.

2-羟基戊二酸介导棕色脂肪细胞变白,并伴随线粒体功能障碍引起的细胞核软化

Kaul Harshita, Isermann Lea, Senft Katharina, Popovic Milica, Georgomanolis Theodoros, Baumann Linda, Sivanesan Pujyanathan, Pouikli Andromachi, Nolte Hendrik, Lucic Bojana, Hildebrandt Ximena, Seidel Katrin, Gnad Thorsten, Gaedke Felix, Göbel Ulrike, Peters Franziska, Cherevatenko Maksym, Park Joo Hyun, Schauss Astrid, Peltzer Nieves, Brüning Jens Claus, Kornfeld Jan-Wilhelm, Pfeifer Alexander, Langer Thomas, Lusic Marina, Wickström Sara A, Frezza Christian, Trifunovic Aleksandra

Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR

线粒体应激的适应需要CHOP介导的ISR调节。

Kaspar, Sophie; Oertlin, Christian; Szczepanowska, Karolina; Kukat, Alexandra; Senft, Katharina; Lucas, Christina; Brodesser, Susanne; Hatzoglou, Maria; Larsson, Ola; Topisirovic, Ivan; Trifunovic, Aleksandra

Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity

UCP2 的缺失可减轻线粒体功能障碍,而不改变活性氧(ROS)的产生和解偶联活性。

Kukat, Alexandra; Dogan, Sukru Anil; Edgar, Daniel; Mourier, Arnaud; Jacoby, Christoph; Maiti, Priyanka; Mauer, Jan; Becker, Christina; Senft, Katharina; Wibom, Rolf; Kudin, Alexei P; Hultenby, Kjell; Flögel, Ulrich; Rosenkranz, Stephan; Ricquier, Daniel; Kunz, Wolfram S; Trifunovic, Aleksandra