日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Stretching the structural envelope of imatinib to reduce β-amyloid production by modulating both β- and γ-secretase cleavages of APP

通过调节APP的β-和γ-分泌酶切割，扩展伊马替尼的结构范围，从而减少β-淀粉样蛋白的生成。

期刊:Frontiers in Chemistry
影响因子:4.2
doi:10.3389/fchem.2024.1381205
Netzer, William J; Sinha, Anjana; Ghias, Mondana; Chang, Emily; Gindinova, Katherina; Mui, Emily; Seo, Ji-Seon; Sinha, Subhash C
APP
发表日期：2024
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Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics.

利用小分子和病毒RNA模拟物促进的靶向蛋白质降解，生成宿主导向和病毒特异性抗病毒药物

期刊:Cell Host & Microbe
影响因子:18.7
doi:10.1016/j.chom.2023.05.030
Zhao Nan, Ho Jessica Sook Yuin, Meng Fanye, Zheng Simin, Kurland Andrew P, Tian Lu, Rea-Moreno Martha, Song Xiangyang, Seo Ji-Seon, Kaniskan H Ümit, Te Velthuis Aartjan J W, Tortorella Domenico, Chen Ya-Wen, Johnson Jeffrey R, Jin Jian, Marazzi Ivan
其它
Viral
血管生成
发表日期：2023
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Ependymal cells-CSF flow regulates stress-induced depression

室管膜细胞-脑脊液流动调节应激诱导的抑郁症

期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-021-01202-1
Seo, Ji-Seon; Mantas, Ioannis; Svenningsson, Per; Greengard, Paul
细胞生物学
抑郁症
神经科学
发表日期：2021
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Amelioration of autism-like social deficits by targeting histone methyltransferases EHMT1/2 in Shank3-deficient mice

通过靶向组蛋白甲基转移酶 EHMT1/2 改善 Shank3 缺陷小鼠的自闭症样社交缺陷

期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-019-0351-2
Wang, Zi-Jun; Zhong, Ping; Ma, Kaijie; Seo, Ji-Seon; Yang, Fengwei; Hu, Zihua; Zhang, Freddy; Lin, Lin; Wang, Jie; Liu, Tao; Matas, Emmanuel; Greengard, Paul; Yan, Zhen
自闭症
EHMT1
神经科学
发表日期：2020
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SEALONE (Safety and Efficacy of Coronary Computed Tomography Angiography with Low Dose in Patients Visiting Emergency Room) trial: study protocol for a randomized controlled trial

SEALONE（低剂量冠状动脉计算机断层扫描血管造影术在急诊患者中的安全性和有效性）试验：一项随机对照试验的研究方案

期刊:Clinical and Experimental Emergency Medicine
影响因子:2.3
doi:10.15441/ceem.17.245
Kim, Joonghee; Kang, Joon-Won; Kim, Kyuseok; Choi, Sang Il; Chun, Eun Ju; Kim, Yeo Goon; Kim, Won Young; Seo, Dong Woo; Shin, Jonghwan; Lee, Huijai; Jin, Kwang-Nam; Ahn, Soyeon; Hwang, Seung Sik; Kim, Kwang Pyo; Jeong, Ru-Bi; Ha, Sang Ook; Choi, Byungho; Yoon, Chang-Hwan; Suh, Jung-Won; Kim, Hack-Lyoung; Kim, Ju Kyoung; Jang, Sujin; Seo, Ji Seon
发表日期：2017
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miR-17-92 Cluster Regulates Adult Hippocampal Neurogenesis, Anxiety, and Depression

miR-17-92簇调控成年海马神经发生、焦虑和抑郁

期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2016.06.101
Jin, Junghee; Kim, Seung-Nam; Liu, Xuqing; Zhang, Haijun; Zhang, Chao; Seo, Ji-Seon; Kim, Yong; Sun, Tao
信号转导
Hippo
神经科学
发表日期：2016
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Rosmarinic Acid Alleviates Neurological Symptoms in the G93A-SOD1 Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

迷迭香酸可缓解肌萎缩侧索硬化症G93A-SOD1转基因小鼠模型的神经系统症状

期刊:Experimental Neurobiology
影响因子:2.1
doi:10.5607/en.2015.24.4.341
Seo, Ji-Seon; Choi, Juli; Leem, Yea-Hyun; Han, Pyung-Lim
SOD1
Mouse
发表日期：2015
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SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action

SMARCA3是一种染色质重塑因子，是p11依赖性抗抑郁作用所必需的。

期刊:Cell
影响因子:42.5
doi:10.1016/j.cell.2013.01.014
Oh, Yong-Seok; Gao, Pu; Lee, Ko-Woon; Ceglia, Ilaria; Seo, Ji-Seon; Zhang, Xiaozhu; Ahn, Jung-Hyuck; Chait, Brian T; Patel, Dinshaw J; Kim, Yong; Greengard, Paul
ARC
表观遗传
神经科学
染色质重塑
发表日期：2013
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NADPH oxidase mediates depressive behavior induced by chronic stress in mice

NADPH氧化酶介导小鼠慢性应激诱导的抑郁行为

期刊:Journal of Neuroscience
影响因子:4
doi:10.1523/JNEUROSCI.0794-12.2012
Seo, Ji-Seon; Park, Jin-Young; Choi, Juli; Kim, Tae-Kyung; Shin, Joo-Hyun; Lee, Ja-Kyeong; Han, Pyung-Lim
神经科学
发表日期：2012
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The nuclear inclusion a (NIa) protease of turnip mosaic virus (TuMV) cleaves amyloid-β.

芜菁花叶病毒 (TuMV) 的核内含物 a (NIa) 蛋白酶可切割淀粉样蛋白-β

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0015645
Han Hye-Eun, Sellamuthu Saravanan, Shin Bae Hyun, Lee Yong Jae, Song Sungmin, Seo Ji-Seon, Baek In-Sun, Bae Jeomil, Kim Hannah, Yoo Yung Joon, Jung Yong-Keun, Song Woo Keun, Han Pyung-Lim, Park Woo Jin
其它
发表日期：2010
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