Genetic knockdown of DYRK1A attenuates cognitive impairment, Aβ pathology, tauopathy and neuroinflammatory responses in mouse models of AD
在阿尔茨海默病小鼠模型中，DYRK1A基因敲低可减轻认知障碍、Aβ病理、tau蛋白病变和神经炎症反应。
期刊:Frontiers in Immunology
影响因子:5.7
doi:10.3389/fimmu.2025.1661791.
Hyun-Ju Lee #,Sora Kang #,Yoo Jin Lee #,Seokjun Oh #,Bitna Joo,Jeong-Woo Hwang,Jeongseop Kim,Tae-Eun Kim,Tae-Mi Jung,Yu-Jin Kim,Ji-Yeong Jang,Jeong-Heon Song,Ja Wook Koo,Hyang-Sook Hoe
神经炎症
Mouse
神经科学
炎症/感染
DYR
DYRK1A
TAU
炎症
