日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A novel HDAC6 inhibitor, CKD-504, is effective in treating preclinical models of huntington's disease

一种新型HDAC6抑制剂CKD-504在治疗亨廷顿病临床前模型中有效。

Li, Endan; Choi, Jiwoo; Sim, Hye-Ri; Kim, Jiyeon; Jun, Jae Hyun; Kyung, Jangbeen; Ha, Nina; Kim, Semi; Ryu, Keun Ho; Chung, Seung Soo; Kim, Hyun Sook; Lee, Sungsu; Seol, Wongi; Song, Jihwan

Urinary Biomarkers for Neurodegenerative Diseases

神经退行性疾病的尿液生物标志物

Seol, Wongi; Kim, Hyejung; Son, Ilhong

Rab GTPases as Physiological Substrates of LRRK2 Kinase

Rab GTP酶作为LRRK2激酶的生理底物

Seol, Wongi; Nam, Daleum; Son, Ilhong

Correction to: Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression

更正:富含亮氨酸重复序列激酶2 (LRRK2) 磷酸化p53并诱导p21(WAF1/CIP1)表达

Ho, Dong Hwan; Kim, Hyejung; Kim, Jisun; Sim, Hyuna; Ahn, Hyunjun; Kim, Janghwan; Seo, Hyemyung; Chung, Kwang Chul; Park, Bum-Joon; Son, Ilhong; Seol, Wongi

Dexamethasone induces the expression of LRRK2 and α-synuclein, two genes that when mutated cause Parkinson's disease in an autosomal dominant manner.

地塞米松可诱导 LRRK2 和 α-突触核蛋白的表达,这两个基因发生突变时会以常染色体显性遗传的方式导致帕金森病

Park Ji-Min, Ho Dong-Hwan, Yun Hye Jin, Kim Hye-Jung, Lee Chan Hong, Park Sung Woo, Kim Young Hoon, Son Ilhong, Seol Wongi

Coordinate Regulation of Neurite Outgrowth by LRRK2 and Its Interactor, Rab5.

LRRK2 及其相互作用蛋白 Rab5 对神经突生长进行协同调控

Heo Hye Young, Kim Kwang-Soo, Seol Wongi

Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra

黑质中脑多巴胺能神经元中LRRK2基因的表达

Han, Baek-Soo; Iacovitti, Lorraine; Katano, Taku; Hattori, Nobutaka; Seol, Wongi; Kim, Kwang-Soo

Induction and characterization of taxol-resistance phenotypes with a transiently expressed artificial transcriptional activator library

利用瞬时表达的人工转录激活因子库诱导和表征紫杉醇抗性表型

Lee, Dong-ki; Kim, Yong Ha; Kim, Jin-Soo; Seol, Wongi