日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nav1.8 mediates peripheral-to-central nociceptive transmission independently of central presynaptic mechanisms in human DRG-spinal cord circuits

在人类背根神经节-脊髓回路中,Nav1.8 介导外周到中枢的伤害性感受传递,且该过程独立于中枢突触前机制。

Palomino, Seph M; Gabriel, Katherin A; Koduri, Ashwin; Khan, Ibrahim; Syed A, Rahman; Horton, Peter; Khan, Tariq; Cervantes, Anna; Funk, Geoffrey; Shiers, Stephanie; Price, Theodore J; Patwardhan, Amol

Brain Hsp90 Inhibition Mitigates Facial Allodynia in a Rat Model of CSD Headache and Upregulates Endocannabinoid Signaling in the PAG.

脑内 Hsp90 抑制可减轻大鼠皮层扩散性抑制性头痛模型中的面部异常性疼痛,并上调 PAG 中的内源性大麻素信号传导。

Palomino Seph M, Levine Aidan A, Liktor-Busa Erika, Tanguturi Parthasaradhireddy, Streicher John M, Largent-Milnes Tally M

Genetic editing of primary human dorsal root ganglion neurons using CRISPR-Cas9.

利用 CRISPR-Cas9 对人类原代背根神经节神经元进行基因编辑

Palomino Seph M, Gabriel Katherin A, Mwirigi Juliet M, Cervantes Anna, Horton Peter, Funk Geoffrey, Moutal Aubin, Martin Laurent F, Khanna Rajesh, Price Theodore J, Patwardhan Amol

Inhibition of diacylglycerol lipase α induced blood-brain barrier breach in female Sprague-Dawley rats

抑制二酰甘油脂肪酶α引起的雌性Sprague-Dawley大鼠血脑屏障破坏

Erika Liktor-Busa, Aidan A Levine, Sally J Young, Colin Bader, Seph M Palomino, Felipe D Polk, Sarah A Couture, Paulo W Pires, Trent Anderson, Tally M Largent-Milnes

Expansion of OSMR expression and signaling in the human dorsal root ganglion links OSM to neuropathic pain

人类背根神经节中OSMR表达和信号传导的扩展将OSM与神经性疼痛联系起来

Mwirigi, Juliet M; Sankaranarayanan, Ishwarya; Tavares-Ferreira, Diana; Gabriel, Katherin A; Palomino, Seph; Li, Yan; Uhelski, Megan L; Shiers, Stephanie; Franco-Enzástiga, Úrzula; Wangzhou, Andi; Lesnak, Joseph B; Bandaru, Samhita; Shrivastava, Aishni; Inturi, Nikhil; Albrecht, Phillip J; Dockum, Marilyn; Cervantes, Anna M; Horton, Peter; Funk, Geoffrey; North, Robert Y; Tatsui, Claudio Esteves; Corrales, German; Yousuf, Muhammad Saad; Curatolo, Michele; Gereau, Robert W; Patwardhan, Amol; Dussor, Gregory; Dougherty, Patrick M; Rice, Frank L; Price, Theodore J

A molecular map of the human spinal dorsal and ventral horn defines arrangement of neuronal types and glial sex differences

人类脊髓背角和腹角的分子图谱揭示了神经元类型的排列以及神经胶质细胞的性别差异。

Gabriel, Katherin A; Davis, Olivia C; Palomino, Seph M; Ishishita, Satoshi; Poldsam, Helen; Brandon, Jane M; Inturi, Nikhil N; Mydugolam, Hemanth; Khan, Ibrahim O; Selvakumaran, Nethra; Shiers, Stephanie; Yousuf, Muhammad Saad; Vines, Erin; Horton, Peter; Khan, Tariq; Cervantes, Anna; Reese, Jeffrey C; Patwardhan, Amol; Dussor, Gregory; Meyers, Eric; Tavares-Ferreira, Diana; Pool, Allan-Hermann; Price, Theodore J

Excitable Rho dynamics control cell shape and motility by sequentially activating ERM proteins and actomyosin contractility

可兴奋的 Rho 动力学通过依次激活 ERM 蛋白和肌动球蛋白收缩力来控制细胞形状和运动

Seph Marshall-Burghardt, Rodrigo A Migueles-Ramírez, Qiyao Lin, Nada El Baba, Rayan Saada, Mustakim Umar, Kian Mavalwala, Arnold Hayer

Depletion of Endothelial-Derived 2-AG Reduces Blood-Endothelial Barrier Integrity via Alteration of VE-Cadherin and the Phospho-Proteome

内皮来源的 2-AG 的消耗通过改变 VE-钙粘蛋白和磷酸化蛋白质组降低血液内皮屏障的完整性

Aidan A Levine, Erika Liktor-Busa, Shreya Balasubramanian, Seph M Palomino, Anya M Burtman, Sarah A Couture, Austin A Lipinski, Paul R Langlais, Tally M Largent-Milnes

ABHD6 and MAGL control 2-AG levels in the PAG and allodynia in a CSD-induced periorbital model of headache

ABHD6 和 MAGL 控制 PAG 中的 2-AG 水平和 CSD 诱发的眶周头痛模型中的异常性疼痛

Erika Liktor-Busa #, Aidan A Levine #, Seph M Palomino, Simar Singh, Jared Wahl, Todd W Vanderah, Nephi Stella, Tally M Largent-Milnes

Inhibition of HSP90 Preserves Blood-Brain Barrier Integrity after Cortical Spreading Depression

抑制 HSP90 可保持皮质扩散性抑制后的血脑屏障完整性

Seph M Palomino, Aidan A Levine, Jared Wahl, Erika Liktor-Busa, John M Streicher, Tally M Largent-Milnes