Sepic相关文献与解析，生知库 | 链接生命科学的每一步

Non-Hospitalized Patients With Post-COVID Condition and Myopathic Electromyography Findings Show no Difference in Symptom Severity and Clinical Manifestations Compared to Those Without Myopathic Findings

非住院的COVID-19后遗症患者，若存在肌病性肌电图检查结果，其症状严重程度和临床表现与无肌病性肌电图检查结果的患者相比并无差异。

期刊:Muscle & Nerve

影响因子:3.1

doi:10.1002/mus.28319

Sepic, Atif; Tryfonos, Andrea; Rundqvist, Helene; Lundberg, Tommy R; Gustafsson, Thomas; Pourhamidi, Kaveh

发表日期：2025

文献求助收藏

mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway.

mTORC1-CTLH E3 连接酶通过 Pro/N-降解途径调节 HMG-CoA 合成酶 1 的降解

期刊:Molecular Cell

影响因子:16.6

doi:10.1016/j.molcel.2024.04.026

Yi Sang Ah, Sepic Sara, Schulman Brenda A, Ordureau Alban, An Heeseon

Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism

人类 WDR26-CTLH E3 连接酶的非典型底物识别调节前体药物代谢

期刊:Molecular Cell

影响因子:14.5

doi:10.1016/j.molcel.2024.04.014

Karthik V Gottemukkala, Jakub Chrustowicz, Dawafuti Sherpa, Sara Sepic, Duc Tung Vu, Özge Karayel, Eleftheria C Papadopoulou, Annette Gross, Kenji Schorpp, Susanne von Gronau, Kamyar Hadian, Peter J Murray, Matthias Mann, Brenda A Schulman, Arno F Alpi

Functional Limitations and Exercise Intolerance in Patients With Post-COVID Condition: A Randomized Crossover Clinical Trial.

新冠后遗症患者的功能限制和运动不耐受：一项随机交叉临床试验

期刊:Jama Network Open

影响因子:9.7

doi:10.1001/jamanetworkopen.2024.4386

Tryfonos Andrea, Pourhamidi Kaveh, JÃ¶rnÃ¥ker Gustav, Engvall Martin, Eriksson Lisa, Elhallos Sara, Asplund Nicole, Mandic Mirko, Sundblad Patrik, Sepic Atif, Rullman Eric, Hyllienmark Lars, Rundqvist Helene, Lundberg Tommy R, Gustafsson Thomas

Cortactin is in a complex with VE-cadherin and is required for endothelial adherens junction stability through Rap1/Rac1 activation

Cortactin 与 VE-cadherin 形成复合物，通过 Rap1/Rac1 激活来维持内皮黏附连接稳定性

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-024-51269-3

Sina Moztarzadeh, Sara Sepic, Ibrahim Hamad, Jens Waschke, Mariya Y Radeva, Alexander García-Ponce

信号转导

发表日期：2024

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Lack of adducin impairs the stability of endothelial adherens and tight junctions and may be required for cAMP-Rac1-mediated endothelial barrier stabilization

缺乏内皮细胞粘附和紧密连接的稳定性，并且可能是 cAMP-Rac1 介导的内皮屏障稳定所必需的

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-022-18964-5

Sina Moztarzadeh #, Mariya Y Radeva #, Sara Sepic, Katharina Schuster, Ibrahim Hamad, Jens Waschke, Alexander García-Ponce

Plakoglobin does not participate in endothelial barrier stabilization mediated by cAMP.

Plakoglobin 不参与 cAMP 介导的内皮屏障稳定作用

Non-Hospitalized Patients With Post-COVID Condition and Myopathic Electromyography Findings Show no Difference in Symptom Severity and Clinical Manifestations Compared to Those Without Myopathic Findings

非住院的COVID-19后遗症患者，若存在肌病性肌电图检查结果，其症状严重程度和临床表现与无肌病性肌电图检查结果的患者相比并无差异。

mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway.

mTORC1-CTLH E3 连接酶通过 Pro/N-降解途径调节 HMG-CoA 合成酶 1 的降解

Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism

人类 WDR26-CTLH E3 连接酶的非典型底物识别调节前体药物代谢

Functional Limitations and Exercise Intolerance in Patients With Post-COVID Condition: A Randomized Crossover Clinical Trial.

新冠后遗症患者的功能限制和运动不耐受：一项随机交叉临床试验

Cortactin is in a complex with VE-cadherin and is required for endothelial adherens junction stability through Rap1/Rac1 activation

Cortactin 与 VE-cadherin 形成复合物，通过 Rap1/Rac1 激活来维持内皮黏附连接稳定性

Lack of adducin impairs the stability of endothelial adherens and tight junctions and may be required for cAMP-Rac1-mediated endothelial barrier stabilization

缺乏内皮细胞粘附和紧密连接的稳定性，并且可能是 cAMP-Rac1 介导的内皮屏障稳定所必需的