日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Vaccine targeting to mucosal lymphoid tissues promotes humoral immunity in the gastrointestinal tract

针对粘膜淋巴组织的疫苗可促进胃肠道体液免疫

Ozgun Kocabiyik, Parastoo Amlashi, A Lina Vo, Heikyung Suh, Sergio A Rodriguez-Aponte, Neil C Dalvie, J Christopher Love, Raiees Andrabi, Darrell J Irvine

SARS-CoV-2 receptor binding domain displayed on HBsAg virus-like particles elicits protective immunity in macaques

HBsAg 病毒样颗粒上展示的 SARS-CoV-2 受体结合域在恒河猴中引发保护性免疫

Neil C Dalvie, Lisa H Tostanoski, Sergio A Rodriguez-Aponte, Kawaljit Kaur, Sakshi Bajoria, Ozan S Kumru, Amanda J Martinot, Abishek Chandrashekar, Katherine McMahan, Noe B Mercado, Jingyou Yu, Aiquan Chang, Victoria M Giffin, Felix Nampanya, Shivani Patel, Lesley Bowman, Christopher A Naranjo, Dong

Steric accessibility of the N-terminus improves the titer and quality of recombinant proteins secreted from Komagataella phaffii

端的空间可及性提高了 Komagataella phaffii 分泌的重组蛋白的滴度和质量

Neil C Dalvie #, Christopher A Naranjo #, Sergio A Rodriguez-Aponte #, Ryan S Johnston, J Christopher Love

RBD-VLP Vaccines Adjuvanted with Alum or SWE Protect K18-hACE2 Mice against SARS-CoV-2 VOC Challenge

以明矾或 SWE 为佐剂的 RBD-VLP 疫苗可保护 K18-hACE2 小鼠免受 SARS-CoV-2 VOC 攻击

Ting Y Wong, Brynnan P Russ, Katherine S Lee, Olivia A Miller, Jason Kang, Melissa Cooper, Michael T Winters, Sergio A Rodriguez-Aponte, Neil C Dalvie, Ryan S Johnston, Nathaniel A Rader, Zeriel Y Wong, Holly A Cyphert, Ivan Martinez, Umesh Shaligram, Saurabh Batwal, Rakesh Lothe, Rahul Chandrasekar

Scalable, methanol-free manufacturing of the SARS-CoV-2 receptor-binding domain in engineered Komagataella phaffii

在工程化的 Komagataella phaffii 中可扩展、无甲醇制造 SARS-CoV-2 受体结合域

Neil C Dalvie, Andrew M Biedermann, Sergio A Rodriguez-Aponte, Christopher A Naranjo, Harish D Rao, Meghraj P Rajurkar, Rakesh R Lothe, Umesh S Shaligram, Ryan S Johnston, Laura E Crowell, Seraphin Castelino, Mary K Tracey, Charles A Whittaker, J Christopher Love

Antigen-adjuvant interactions, stability, and immunogenicity profiles of a SARS-CoV-2 receptor-binding domain (RBD) antigen formulated with aluminum salt and CpG adjuvants

用铝盐和 CpG 佐剂配制的 SARS-CoV-2 受体结合域 (RBD) 抗原的抗原佐剂相互作用、稳定性和免疫原性特征

Sakshi Bajoria, Kawaljit Kaur, Ozan S Kumru, Greta Van Slyke, Jennifer Doering, Hayley Novak, Sergio A Rodriguez Aponte, Neil C Dalvie, Christopher A Naranjo, Ryan S Johnston, Judith Maxwell Silverman, Harry Kleanthous, J Christopher Love, Nicholas J Mantis, Sangeeta B Joshi, David B Volkin

Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2

磷酸盐介导的RBD免疫原和分子佐剂与明矾的共锚定可增强针对SARS-CoV-2的体液免疫。

Kristen A Rodrigues ,Sergio A Rodriguez-Aponte ,Neil C Dalvie ,Jeong Hyun Lee ,Wuhbet Abraham ,Diane G Carnathan ,Luis E Jimenez ,Julia T Ngo ,Jason Y H Chang ,Zeli Zhang ,Jingyou Yu ,Aiquan Chang ,Catherine Nakao ,Benjamin Goodwin ,Christopher A Naranjo ,Libin Zhang ,Murillo Silva ,Dan H Barouch ,Guido Silvestri ,Shane Crotty ,J Christopher Love ,Darrell J Irvine

Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus

分子工程提高抗原质量并实现轮状病毒三价亚单位候选疫苗的一体化生产

Neil C Dalvie #, Joseph R Brady #, Laura E Crowell, Mary Kate Tracey, Andrew M Biedermann, Kawaljit Kaur, John M Hickey, D Lee Kristensen 2nd, Alexandra D Bonnyman, Sergio A Rodriguez-Aponte, Charles A Whittaker, Marina Bok, Celina Vega, Tarit K Mukhopadhyay, Sangeeta B Joshi, David B Volkin, Vivian

Scalable, methanol-free manufacturing of the SARS-CoV-2 receptor binding domain in engineered Komagataella phaffii

在工程化的 Komagataella phaffii 中可扩展、无甲醇制造 SARS-CoV-2 受体结合域

Neil C Dalvie #, Andrew M Biedermann #, Sergio A Rodriguez-Aponte, Christopher A Naranjo, Harish D Rao, Meghraj P Rajurkar, Rakesh R Lothe, Umesh S Shaligram, Ryan S Johnston, Laura E Crowell, Seraphin Castelino, Mary Kate Tracey, Charles A Whittaker, J Christopher Love

Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters

工程化的 SARS-CoV-2 受体结合域可改善小鼠的免疫原性并在仓鼠中引发保护性免疫

Neil C Dalvie, Sergio A Rodriguez-Aponte, Brittany L Hartwell, Lisa H Tostanoski, Andrew M Biedermann, Laura E Crowell, Kawaljit Kaur, Ozan Kumru, Lauren Carter, Jingyou Yu, Aiquan Chang, Katherine McMahan, Thomas Courant, Celia Lebas, Ashley A Lemnios, Kristen A Rodrigues, Murillo Silva, Ryan S Joh