日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Antimalarial Drug Combination Predictions Using the Machine Learning Synergy Predictor (MLSyPred©) tool

利用机器学习协同预测器 (MLSyPred©) 工具进行抗疟疾药物组合预测

Roche-Lima, Abiel; Rosado-Quiñones, Angélica M; Feliu-Maldonado, Roberto A; Figueroa-Gispert, María Del Mar; Díaz-Rivera, Jennifer; Díaz-González, Roberto G; Carrasquillo-Carrion, Kelvin; Nieves, Brenda G; Colón-Lorenzo, Emilee E; Serrano, Adelfa E

Two Gracilioethers Containing a [2(5H)-Furanylidene]ethanoate Moiety and 9,10-Dihydroplakortone G: New Polyketides from the Caribbean Marine Sponge Plakortis halichondrioides

两种含有[2(5H)-呋喃亚甲基]乙酸酯部分的纤细醚和9,10-二氢plakortone G:来自加勒比海海洋海绵Plakortis halichondrioides的新型聚酮化合物

Amador, Luis A; Rodríguez, Abimael D; Carmona-Sarabia, Lesly; Colón-Lorenzo, Emilee E; Serrano, Adelfa E

Glutathione-deficient Plasmodium berghei parasites exhibit growth delay and nuclear DNA damage

缺乏谷胱甘肽的伯氏疟原虫表现出生长迟缓和核DNA损伤。

Padín-Irizarry, Vivian; Colón-Lorenzo, Emilee E; Vega-Rodríguez, Joel; Castro, María Del R; González-Méndez, Ricardo; Ayala-Peña, Sylvette; Serrano, Adelfa E

Implications of Glutathione Levels in the Plasmodium berghei Response to Chloroquine and Artemisinin

谷胱甘肽水平对伯氏疟原虫氯喹和青蒿素反应的影响

Vega-Rodríguez, Joel; Pastrana-Mena, Rebecca; Crespo-Lladó, Keila N; Ortiz, José G; Ferrer-Rodríguez, Iván; Serrano, Adelfa E

Diversity-oriented synthesis-facilitated medicinal chemistry: toward the development of novel antimalarial agents

以多样性为导向的合成促进药物化学:迈向新型抗疟药物的开发

Comer, Eamon; Beaudoin, Jennifer A; Kato, Nobutaka; Fitzgerald, Mark E; Heidebrecht, Richard W; Lee, Maurice duPont 4th; Masi, Daniela; Mercier, Marion; Mulrooney, Carol; Muncipinto, Giovanni; Rowley, Ann; Crespo-Llado, Keila; Serrano, Adelfa E; Lukens, Amanda K; Wiegand, Roger C; Wirth, Dyann F; Palmer, Michelle A; Foley, Michael A; Munoz, Benito; Scherer, Christina A; Duvall, Jeremy R; Schreiber, Stuart L

A concise silylamine approach to 2-amino-3-hydroxy-indoles with potent in vivo antimalaria activity

一种简洁的硅烷胺化方法合成具有强效体内抗疟活性的2-氨基-3-羟基吲哚类化合物

Urgaonkar, Sameer; Cortese, Joseph F; Barker, Robert H; Cromwell, Mandy; Serrano, Adelfa E; Wirth, Dyann F; Clardy, Jon; Mazitschek, Ralph

Glutathione reductase-null malaria parasites have normal blood stage growth but arrest during development in the mosquito.

缺乏谷胱甘肽还原酶的疟原虫在血液期生长正常,但在蚊子体内发育过程中会停止

Pastrana-Mena Rebecca, Dinglasan Rhoel R, Franke-Fayard Blandine, Vega-Rodríguez Joel, Fuentes-Caraballo Mariela, Baerga-Ortiz Abel, Coppens Isabelle, Jacobs-Lorena Marcelo, Janse Chris J, Serrano Adelfa E

Identification and bioinformatic characterization of a multidrug resistance associated protein (ABCC) gene in Plasmodium berghei

伯氏疟原虫多药耐药相关蛋白(ABCC)基因的鉴定和生物信息学表征

González-Pons, María; Szeto, Ada C; González-Méndez, Ricardo; Serrano, Adelfa E