日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of a Pseudomonas aeruginosa-specific small molecule targeting outer membrane protein OprH-LPS interaction by a multiplexed screen.

通过多重筛选发现了一种靶向铜绿假单胞菌外膜蛋白 OprH-LPS 相互作用的小分子

Poulsen Bradley E, Warrier Thulasi, Barkho Sulyman, Bagnall Josephine, Romano Keith P, White Tiantian, Yu Xiao, Kawate Tomohiko, Nguyen Phuong H, Raines Kyra, Ferrara Kristina, Golas A Lorelei, FitzGerald Michael, Boeszoermenyi Andras, Kaushik Virendar, Serrano-Wu Michael, Shoresh Noam, Hung Deborah T

Evaluation of expanded 2-aminobenzothiazole library as inhibitors of a model histidine kinase and virulence suppressors in Pseudomonas aeruginosa.

评估扩展的 2-氨基苯并噻唑化合物库作为模型组氨酸激酶抑制剂和铜绿假单胞菌毒力抑制剂的活性

Fihn Conrad A, Lembke Hannah K, Gaulin Jeffrey, Bouchard Patricia, Villarreal Alex R, Penningroth Mitchell R, Crone Kathryn K, Vogt Grace A, Gilbertsen Adam J, Ayotte Yann, Coutinho de Oliveira Luciana, Serrano-Wu Michael H, Drouin Nathalie, Hung Deborah T, Hunter Ryan C, Carlson Erin E

Allosteric MAPKAPK2 inhibitors improve plaque stability in advanced atherosclerosis

变构MAPKAPK2抑制剂可改善晚期动脉粥样硬化斑块的稳定性

Ozcan, Lale; Kasikara, Canan; Yurdagul, Arif Jr; Kuriakose, George; Hubbard, Brian; Serrano-Wu, Michael H; Tabas, Ira

Discovery of heterocyclic replacements for the coumarin core of anti-tubercular FadD32 inhibitors

发现用于替代抗结核药物 FadD32 抑制剂香豆素核心的杂环化合物

Fang, Chao; Lee, Katie K; Nietupski, Raymond; Bates, Robert H; Fernandez-Menendez, Raquel; Lopez-Roman, Eva Maria; Guijarro-Lopez, Laura; Yin, Yunxing; Peng, Zuozhong; Gomez, James E; Fisher, Stewart; Barros-Aguirre, David; Hubbard, Brian K; Serrano-Wu, Michael H; Hung, Deborah T

Inhibitors of HCV NS5A: From Iminothiazolidinones to Symmetrical Stilbenes

HCV NS5A抑制剂:从亚氨基噻唑烷酮类到对称芪类

Romine, Jeffrey L; St Laurent, Denis R; Leet, John E; Martin, Scott W; Serrano-Wu, Michael H; Yang, Fukang; Gao, Min; O'Boyle, Donald R 2nd; Lemm, Julie A; Sun, Jin-Hua; Nower, Peter T; Huang, Xiaohua Stella; Deshpande, Milind S; Meanwell, Nicholas A; Snyder, Lawrence B