日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein

符合 BSL2 标准的 SARS-CoV-2 致死小鼠模型及其受关注的变异株,用于评估针对刺突蛋白的治疗方法

Mohanraj Manangeeswaran, Derek D C Ireland, Seth G Thacker, Ha-Na Lee, Logan Kelley-Baker, Aaron P Lewkowicz, Paul W Rothlauf, Marjorie Cornejo Pontelli, Louis-Marie Bloyet, Michael A Eckhaus, Mirian I Mendoza, Sean Whelan, Daniela Verthelyi

Elevated interleukin-10: a new cause of dyslipidemia leading to severe HDL deficiency

白细胞介素-10 升高:导致严重高密度脂蛋白缺乏症的血脂异常新原因

Andreas G Moraitis, Lita A Freeman, Robert D Shamburek, Robert Wesley, Wyndham Wilson, Cliona M Grant, Susan Price, Stephen Demosky, Seth G Thacker, Abdalrahman Zarzour, Ronald L Hornung, Frank Pucino, Gyorgy Csako, Cheryl Yarboro, Iain B McInnes, Takashi Kuroiwa, Dimitrios Boumpas, V Koneti Rao, Ga

Synthesis of cholesterol analogues bearing BODIPY fluorophores by Suzuki or Liebeskind-Srogl cross-coupling and evaluation of their potential for visualization of cholesterol pools

通过 Suzuki 或 Liebeskind-Srogl 交叉偶联合成带有 BODIPY 荧光团的胆固醇类似物并评估其对胆固醇池可视化的潜力

Zheng Liu, Seth G Thacker, Sara Fernandez-Castillejo, Edward B Neufeld, Alan T Remaley, Robert Bittman

Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus

炎症小体激活 IL-18 导致系统性红斑狼疮内皮祖细胞功能障碍

J Michelle Kahlenberg, Seth G Thacker, Celine C Berthier, Clemens D Cohen, Matthias Kretzler, Mariana J Kaplan

The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction

IFN-α 对狼疮血管生成的有害影响是由 IL-1 通路抑制介导的:在动脉粥样硬化形成和肾血管稀疏中的潜在作用

Seth G Thacker, Celine C Berthier, Deborah Mattinzoli, Maria Pia Rastaldi, Matthias Kretzler, Mariana J Kaplan

A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs

从系统性红斑狼疮患者中分离出的促炎性中性粒细胞的一个独特亚群会诱发血管损伤并合成 I 型干扰素

Michael F Denny, Srilakshmi Yalavarthi, Wenpu Zhao, Seth G Thacker, Marc Anderson, Ashley R Sandy, W Joseph McCune, Mariana J Kaplan

The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus

过氧化物酶体增殖激活受体γ激动剂吡格列酮可改善小鼠狼疮的心脏代谢风险和肾脏炎症

Wenpu Zhao, Seth G Thacker, Jeffrey B Hodgin, Hongyu Zhang, Jeffrey H Wang, James L Park, Ann Randolph, Emily C Somers, Subramaniam Pennathur, Matthias Kretzler, Frank C Brosius 3rd, Mariana J Kaplan

Interactions of T cells with fibroblast-like synoviocytes: role of the B7 family costimulatory ligand B7-H3

细胞与成纤维细胞样滑膜细胞的相互作用:B7 家族共刺激配体 B7-H3 的作用

Chinh N Tran, Seth G Thacker, Deanna M Louie, Jennifer Oliver, Peter T White, Judith L Endres, Andrew G Urquhart, Kevin C Chung, David A Fox