日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multiscale modelling of relationships between protein classes and drug behavior across all diseases using the CANDO platform

利用 CANDO 平台对所有疾病中蛋白质类别与药物行为之间的关系进行多尺度建模

Sethi, Geetika; Chopra, Gaurav; Samudrala, Ram

PTN signaling: Components and mechanistic insights in human ovarian cancer.

PTN信号传导:人类卵巢癌的组成成分和机制见解

Sethi Geetika, Kwon Youngjoo, Burkhalter Rebecca J, Pathak Harsh B, Madan Rashna, McHugh Sarah, Atay Safinur, Murthy Smruthi, Tawfik Ossama W, Godwin Andrew K

A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer

利用靶向siRNA文库进行合成致死筛选,以鉴定对达沙替尼治疗上皮性卵巢癌敏感的药物

Pathak, Harsh B; Zhou, Yan; Sethi, Geetika; Hirst, Jeff; Schilder, Russell J; Golemis, Erica A; Godwin, Andrew K

CANDO and the infinite drug discovery frontier

CANDO 与无限的药物发现前沿

Minie, Mark; Chopra, Gaurav; Sethi, Geetika; Horst, Jeremy; White, George; Roy, Ambrish; Hatti, Kaushik; Samudrala, Ram

An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer

利用RNA干扰致死性筛选人类可药物靶向基因组,以识别上皮性卵巢癌的分子脆弱性

Sethi, Geetika; Pathak, Harsh B; Zhang, Hong; Zhou, Yan; Einarson, Margret B; Vathipadiekal, Vinod; Gunewardena, Sumedha; Birrer, Michael J; Godwin, Andrew K