日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetic mapping identifies Homer1 as a developmental modifier of attention

基因定位显示Homer1是注意力发育的调节因子。

Gershon, Zachary; Bonito-Oliva, Alessandra; Kanke, Matt; Terceros, Andrea; Rankin, Genelle; Fak, John; Harada, Yujin; Iannone, Andrew F; Gebremedhin, Millennium; Fabella, Brian; De Marco García, Natalia V; Sethupathy, Praveen; Rajasethupathy, Priya

Correction: DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma

更正:DNAJB1-PRKACA融合蛋白调控的LINC00473促进纤维板层癌的肿瘤生长并改变线粒体功能

Ma, Rosanna K; Tsai, Pei-Yin; Farghli, Alaa R; Shumway, Alexandria; Kanke, Matt; Gordan, John D; Gujral, Taranjit S; Vakili, Khashayar; Nukaya, Manabu; Noetzli, Leila; Ronnekleiv-Kelly, Sean; Broom, Wendy; Barrow, Joeva; Sethupathy, Praveen

Decellularized liver scaffolds for constructing drug-metabolically functional ex vivo human liver models.

用于构建具有药物代谢功能的离体人肝模型的脱细胞肝脏支架

Liu Juan, Hanson Ariel, Yin Wenzhen, Wu Qiao, Wauthier Eliane, Diao Jinmei, Dinh Timothy, Macdonald Jeff, Li Ruihong, Terajima Masahiko, Yamauchi Mitsuo, Chen Ziye, Sethupathy Praveen, Dong Jiahong, Reid Lola M, Wang Yunfang

Extensive differential gene expression and regulation by sex in human skeletal muscle

人类骨骼肌中广泛的差异基因表达和性别调控

Hanks, Sarah C; Mauger, Abigail S; Varshney, Arushi; Ciotlos, Dan L; Manickam, Nandini; Narisu, Narisu; Shumway, Alexandria J; Orchard, Peter; Erdos, Michael R; Sweeney, Michael D; Okamoto, Jeffrey; Jackson, Anne U; Stringham, Heather M; Bonnycastle, Lori L; Zhou, Xiang; Lakka, Timo A; Mohlke, Karen L; Tuomilehto, Jaakko; Laakso, Markku; Boehnke, Michael; Sethupathy, Praveen; Collins, Francis S; Koistinen, Heikki A; Parker, Stephen C J; Scott, Laura J

The diabetes gene Tcf7l2 organizes gene expression in the liver and regulates amino acid metabolism.

糖尿病基因Tcf7l2在肝脏中组织基因表达并调节氨基酸代谢

Krawczyk Joanna, O'Connor William, Vendramini Pedro, Schell Mareike, Biddinger Kiran J, Kanke Matt, Pengo George, Semova Ivana, Fougeray Tiffany, Haigis Marcia, Aragam Krishna G, Lamers Wouter H, Tsai Linus T, Sethupathy Praveen, Biddinger Sudha B

A novel high-throughput screening platform to identify inhibitors of DNAJB1-PRKACA-driven transcriptional activity in fibrolamellar carcinoma.

一种新型高通量筛选平台,用于鉴定纤维板层癌中 DNAJB1-PRKACA 驱动的转录活性的抑制剂

Bharath Nihal, DiPietro Emma, Durfee Olivia, Kycia Ina, Splaine Jennifer, Sethupathy Praveen, Rogers Michael S, Vakili Khashayar

Intestinal epithelial adaptations to vertical sleeve gastrectomy defined at single-cell resolution

单细胞分辨率下肠上皮对垂直袖状胃切除术的适应性变化

Koch-Laskowski, Kieran; Kim, Ki-Suk; Bethea, Maigen; Fuller, Kelly N Z; Sandoval, Darleen A; Sethupathy, Praveen

Single-cell multi-omic analysis of fibrolamellar carcinoma reveals rewired cell-to-cell communication patterns and unique vulnerabilities

对纤维板层癌的单细胞多组学分析揭示了细胞间通讯模式的重塑和独特的脆弱性

Farghli, Alaa R; Chan, Marina; Sherman, Marc S; Dickerson, Lindsay K; Shui, Bo; Nukaya, Manabu; Stephanou, Andreas; Ma, Rosanna K; Pepe-Mooney, Brian J; Smith, Colton J; Long, Donald; Munn, Paul R; McNairn, Adrian; Grenier, Jennifer K; Karski, Michael; Ronnekleiv-Kelly, Sean M; Pillarisetty, Venu G; Goessling, Wolfram; Gujral, Taranjit S; Vakili, Khashayar; Sethupathy, Praveen

Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis

大规模遗传分析揭示了与糖尿病及相关性状相关的人类胰岛微RNA

Taylor, Henry J; Hung, Yu-Han; Narisu, Narisu; Erdos, Michael R; Kanke, Matthew; Yan, Tingfen; Grenko, Caleb M; Swift, Amy J; Bonnycastle, Lori L; Sethupathy, Praveen; Collins, Francis S; Taylor, D Leland

Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes β-Cell IGF-I Signaling

维拉帕米可预防1型糖尿病患者IGF-I水平下降并促进β细胞IGF-I信号传导

Xu, Guanlan; Chen, Junqin; Lu, Brian; Sethupathy, Praveen; Qian, Wei-Jun; Shalev, Anath