日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Inhibition of Aurora Kinase Induces Endogenous Retroelements to Induce a Type I/III IFN Response via RIG-I

抑制极光激酶可诱导内源性逆转录元件通过RIG-I诱导I/III型干扰素反应。

期刊:Cancer Research Communications
影响因子:3.3
doi:10.1158/2767-9764.CRC-23-0432
Choy, Lisa; Norris, Stephen; Wu, Xiumin; Kolumam, Ganesh; Firestone, Ari; Settleman, Jeffrey; Stokoe, David
信号转导
发表日期：2024
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Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity

EGFR突变型肺癌对酪氨酸激酶抑制剂治疗的获得性耐药促进PARP抑制剂的敏感性

期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2019.05.058
Lynnette Marcar ,Kankana Bardhan ,Liliana Gheorghiu ,Patrick Dinkelborg ,Heike Pfäffle ,Qi Liu ,Meng Wang ,Zofia Piotrowska ,Lecia V Sequist ,Kerstin Borgmann ,Jeffrey E Settleman ,Jeffrey A Engelman ,Aaron N Hata ,Henning Willers
肺癌
信号转导
肿瘤
EGFR
肿瘤免疫
EGF
PARP
发表日期：2019
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Challenges in validating candidate therapeutic targets in cancer

癌症候选治疗靶点验证面临的挑战

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.32402
Settleman, Jeffrey; Sawyers, Charles L; Hunter, Tony
肿瘤
肿瘤免疫
发表日期：2018
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Synthetic lethal interaction of combined BCL-XL and MEK inhibition promotes tumor regressions in KRAS mutant cancer models

BCL-XL 和 MEK 抑制剂联合抑制的合成致死作用可促进 KRAS 突变癌症模型中的肿瘤消退

期刊:Cancer Cell
影响因子:44.5
doi:10.1016/j.ccr.2012.11.007
Corcoran, Ryan B; Cheng, Katherine A; Hata, Aaron N; Faber, Anthony C; Ebi, Hiromichi; Coffee, Erin M; Greninger, Patricia; Brown, Ronald D; Godfrey, Jason T; Cohoon, Travis J; Song, Youngchul; Lifshits, Eugene; Hung, Kenneth E; Shioda, Toshi; Dias-Santagata, Dora; Singh, Anurag; Settleman, Jeffrey; Benes, Cyril H; Mino-Kenudson, Mari; Wong, Kwok-Kin; Engelman, Jeffrey A
RAS
肿瘤
肿瘤免疫
发表日期：2013
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Lateral to End-on Conversion of Chromosome-Microtubule Attachment Requires Kinesins CENP-E and MCAK

染色体-微管连接的侧向到端向转换需要驱动蛋白CENP-E和MCAK

期刊:Current Biology
影响因子:7.5
doi:10.1016/j.cub.2008.09.019
Bustos, Rodrigo I; Forget, Marie-Annick; Settleman, Jeffrey E; Hansen, Steen H; Kobayashi, Shunsuke; Schultz, Wolfram; Shrestha, Roshan L; Draviam, Viji M
发表日期：2013
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Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells

靶向异常谷胱甘肽代谢以根除人类急性髓系白血病细胞

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M113.511170
Pei, Shanshan; Minhajuddin, Mohammad; Callahan, Kevin P; Balys, Marlene; Ashton, John M; Neering, Sarah J; Lagadinou, Eleni D; Corbett, Cheryl; Ye, Haobin; Liesveld, Jane L; O'Dwyer, Kristen M; Li, Zheng; Shi, Lei; Greninger, Patricia; Settleman, Jeffrey; Benes, Cyril; Hagen, Fred K; Munger, Joshua; Crooks, Peter A; Becker, Michael W; Jordan, Craig T
白血病
细胞生物学
代谢
发表日期：2013
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A phase I study of erlotinib and hydroxychloroquine in advanced non-small-cell lung cancer

厄洛替尼联合羟氯喹治疗晚期非小细胞肺癌的I期研究

期刊:Journal of Thoracic Oncology
影响因子:20.8
doi:10.1097/JTO.0b013e318262de4a
Goldberg, Sarah B; Supko, Jeffrey G; Neal, Joel W; Muzikansky, Alona; Digumarthy, Subba; Fidias, Panos; Temel, Jennifer S; Heist, Rebecca S; Shaw, Alice T; McCarthy, Patricia O; Lynch, Thomas J; Sharma, Sreenath; Settleman, Jeffrey E; Sequist, Lecia V
肺癌
细胞生物学
肿瘤
肿瘤免疫
发表日期：2012
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EGFR ligands exhibit functional differences in models of paracrine and autocrine signaling.

EGFR 配体在旁分泌和自分泌信号模型中表现出功能差异

期刊:Growth Factors
影响因子:1.7
doi:10.3109/08977194.2011.649918
Wilson Kristy J, Mill Christopher, Lambert Sydney, Buchman Jennifer, Wilson Timothy R, Hernandez-Gordillo Victor, Gallo Richard M, Ades Laura M C, Settleman Jeffrey, Riese David J 2nd
信号转导
EGFR
发表日期：2012
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A chemical biology approach to developing STAT inhibitors: molecular strategies for accelerating clinical translation

利用化学生物学方法开发STAT抑制剂：加速临床转化的分子策略

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.296
Nelson, Erik A; Sharma, Sreenath V; Settleman, Jeffrey; Frank, David A
JAK/STAT
发表日期：2011
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Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

快速靶向分析人类肿瘤突变：指导个体化癌症治疗的临床平台

期刊:EMBO Molecular Medicine
影响因子:8.3
doi:10.1002/emmm.201000070
Dias-Santagata, Dora; Akhavanfard, Sara; David, Serena S; Vernovsky, Kathy; Kuhlmann, Georgiana; Boisvert, Susan L; Stubbs, Hannah; McDermott, Ultan; Settleman, Jeffrey; Kwak, Eunice L; Clark, Jeffrey W; Isakoff, Steven J; Sequist, Lecia V; Engelman, Jeffrey A; Lynch, Thomas J; Haber, Daniel A; Louis, David N; Ellisen, Leif W; Borger, Darrell R; Iafrate, A John
肿瘤
肿瘤免疫
发表日期：2010
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