日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genome-wide association study of delay discounting identifies 11 loci and reveals transdiagnostic associations across mental and physical health

全基因组关联研究发现了延迟折扣的11个基因位点,并揭示了其在心理健康和生理健康方面的跨诊断关联。

Thorpe, Hayley H A; Cupertino, Renata B; Pakala, Shreya Reddy; Fontanillas, Pierre; Jennings, Mariela V; Yang, Jane; Meredith, John J; Greenwood, Tiffany; Bianchi, Sevim B; Vilar-Ribó, Laura; Niarchou, Maria; Elson, Sarah L; Ideker, Trey; Davis, Lea K; MacKillop, James; deWit, Harriet; Gustavson, Daniel E; Mallard, Travis T; Palmer, Abraham A; Sanchez-Roige, Sandra

Genomic structural equation study reveals links between anorexia nervosa and delay discounting and lack of perseverance but not other facets of impulsivity

基因组结构方程研究揭示了神经性厌食症与延迟折扣和缺乏毅力之间的联系,但与其他冲动性特征无关。

Bianchi, Sevim B; Vilar-Ribó, Laura; Palmer, Abraham A; Gustavson, Daniel E; Sanchez-Roige, Sandra

Sex-Specific Genetic Architecture and Comorbidities of Alcohol Use Behaviors

性别特异性遗传结构与酒精使用行为的合并症

Vilar-Ribó, Laura; Jennings, Mariela V; Sallah, Aisha; Jinwala, Zeal; Thorpe, Hayley Ha; Bianchi, Sevim B; Meredith, John; Feuer, Kyra; Rader, Lydia; Courchesne-Krak, Natasia; Niarchou, Maria; Balbona, Jared; Elson, Sarah L; Fontanillas, Pierre; Johnson, Emma C; Davis, Lea K; Hatoum, Alexander S; Mallard, Travis T; Gustavson, Daniel E; Zhou, Hang; Palmer, Abraham A; Savage, Jeanne E; Kember, Rachel L; Sanchez-Roige, Sandra

Prescription Opioid Medication Survey: A Tool to Collect Deep Phenotypic Data on the Multifactorial Pathways to Opioid Use Disorder in Clinical and Population-Based Cohorts

处方阿片类药物调查:一种用于收集临床和人群队列中阿片类药物使用障碍多因素途径的深度表型数据的工具

Courchesne-Krak, Natasia S; Chandrasekaran, Anirudh R; Gonzalez, Jean; Bianchi, Sevim B; Tran, Vinh; Johnson, Eric O; Troiani, Vanessa; Hettema, John M; Stein, Murray B; Coon, Hilary; Docherty, Anna R; Berretini, Wade H; MacKillop, James; de Wit, Harriet; Marienfeld, Carla; Palmer, Abraham A; Sanchez-Roige, Sandra

Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes

一项针对烟草使用障碍的多民族荟萃分析,识别出461个潜在风险基因,并揭示了这些基因与多种健康结果的关联。

Toikumo, Sylvanus; Jennings, Mariela V; Pham, Benjamin K; Lee, Hyunjoon; Mallard, Travis T; Bianchi, Sevim B; Meredith, John J; Vilar-Ribó, Laura; Xu, Heng; Hatoum, Alexander S; Johnson, Emma C; Pazdernik, Vanessa K; Jinwala, Zeal; Pakala, Shreya R; Leger, Brittany S; Niarchou, Maria; Ehinmowo, Michael; Jenkins, Greg D; Batzler, Anthony; Pendegraft, Richard; Palmer, Abraham A; Zhou, Hang; Biernacka, Joanna M; Coombes, Brandon J; Gelernter, Joel; Xu, Ke; Hancock, Dana B; Cox, Nancy J; Smoller, Jordan W; Davis, Lea K; Justice, Amy C; Kranzler, Henry R; Kember, Rachel L; Sanchez-Roige, Sandra

A phenome-wide association and Mendelian randomisation study of alcohol use variants in a diverse cohort comprising over 3 million individuals

一项针对包含超过300万个体的多样化队列,开展的全表型关联和孟德尔随机化研究,旨在探究酒精使用相关变异。

Jennings, Mariela V; Martínez-Magaña, José Jaime; Courchesne-Krak, Natasia S; Cupertino, Renata B; Vilar-Ribó, Laura; Bianchi, Sevim B; Hatoum, Alexander S; Atkinson, Elizabeth G; Giusti-Rodriguez, Paola; Montalvo-Ortiz, Janitza L; Gelernter, Joel; Artigas, María Soler; Elson, Sarah L; Edenberg, Howard J; Fontanillas, Pierre; Palmer, Abraham A; Sanchez-Roige, Sandra

Genome-wide association studies of coffee intake in UK/US participants of European ancestry uncover cohort-specific genetic associations

针对英国/美国欧洲裔参与者咖啡摄入量的全基因组关联研究揭示了特定人群的遗传关联

Thorpe, Hayley H A; Fontanillas, Pierre; Pham, Benjamin K; Meredith, John J; Jennings, Mariela V; Courchesne-Krak, Natasia S; Vilar-Ribó, Laura; Bianchi, Sevim B; Mutz, Julian; Elson, Sarah L; Khokhar, Jibran Y; Abdellaoui, Abdel; Davis, Lea K; Palmer, Abraham A; Sanchez-Roige, Sandra

RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells

RAC1B的功能对于乳腺癌干细胞的维持和乳腺肿瘤细胞的化疗耐药性至关重要。

Chen, Fuhui; Gurler, Sevim B; Novo, David; Selli, Cigdem; Alferez, Denis G; Eroglu, Secil; Pavlou, Kyriaki; Zhang, Jingwei; Sims, Andrew H; Humphreys, Neil E; Adamson, Antony; Campbell, Andrew; Sansom, Owen J; Tournier, Cathy; Clarke, Robert B; Brennan, Keith; Streuli, Charles H; Ucar, Ahmet

CADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice

基因组和表型组关联研究表明,CADM2与冲动型人格及其他多种特征有关,这些研究对象包括人类和小鼠。

Sanchez-Roige, Sandra; Jennings, Mariela V; Thorpe, Hayley H A; Mallari, Jazlene E; van der Werf, Lieke C; Bianchi, Sevim B; Huang, Yuye; Lee, Calvin; Mallard, Travis T; Barnes, Samuel A; Wu, Jin Yi; Barkley-Levenson, Amanda M; Boussaty, Ely C; Snethlage, Cedric E; Schafer, Danielle; Babic, Zeljana; Winters, Boyer D; Watters, Katherine E; Biederer, Thomas; Mackillop, James; Stephens, David N; Elson, Sarah L; Fontanillas, Pierre; Khokhar, Jibran Y; Young, Jared W; Palmer, Abraham A

Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes

一项针对烟草使用障碍的多民族荟萃分析,筛选出新的候选风险基因,并揭示了其与多种健康结果的关联。

Toikumo, Sylvanus; Jennings, Mariela V; Pham, Benjamin K; Lee, Hyunjoon; Mallard, Travis T; Bianchi, Sevim B; Meredith, John J; Vilar-Ribó, Laura; Xu, Heng; Hatoum, Alexander S; Johnson, Emma C; Pazdernik, Vanessa; Jinwala, Zeal; Pakala, Shreya R; Leger, Brittany S; Niarchou, Maria; Ehinmowo, Michael; Jenkins, Greg D; Batzler, Anthony; Pendegraft, Richard; Palmer, Abraham A; Zhou, Hang; Biernacka, Joanna M; Coombes, Brandon J; Gelernter, Joel; Xu, Ke; Hancock, Dana B; Cox, Nancy J; Smoller, Jordan W; Davis, Lea K; Justice, Amy C; Kranzler, Henry R; Kember, Rachel L; Sanchez-Roige, Sandra