Sevin Turcan相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Targeting therapeutic vulnerabilities with PARP inhibition and radiation in IDH-mutant gliomas and cholangiocarcinomas

利用 PARP 抑制和放射疗法针对 IDH 突变型胶质瘤和胆管癌的治疗弱点进行治疗

期刊:Science Advances

影响因子:11.7

doi:10.1126/sciadv.aaz3221

Yuxiang Wang, Aaron T Wild, Sevin Turcan, Wei H Wu, Carlie Sigel, David S Klimstra, Xiaoxiao Ma, Yongxing Gong, Eric C Holland, Jason T Huse, Timothy A Chan

发表日期：2020

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Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence

突变IDH1依赖的染色质状态重编程、可逆性和持久性

期刊:Nature Genetics

影响因子:31.7

doi:10.1038/s41588-017-0001-z

Sevin Turcan, Vladimir Makarov, Julian Taranda, Yuxiang Wang, Armida W M Fabius, Wei Wu, Yupeng Zheng, Nour El-Amine, Sara Haddock, Gouri Nanjangud, H Carl LeKaye, Cameron Brennan, Justin Cross, Jason T Huse, Neil L Kelleher, Pavel Osten, Craig B Thompson, Timothy A Chan

发表日期：2018

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Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins

泛癌基因分析表明，PARK2 是 G1/S 细胞周期蛋白的主要调控因子。

期刊:Nature Genetics

影响因子:31.7

doi:10.1038/ng.2981

Yongxing Gong ,Travis Ian Zack ,Luc G T Morris ,Kan Lin ,Ellen Hukkelhoven ,Radhika Raheja ,I-Li Tan ,Sevin Turcan ,Selvaraju Veeriah ,Shasha Meng ,Agnes Viale ,Steven E Schumacher ,Perry Palmedo ,Rameen Beroukhim ,Timothy A Chan

细胞生物学

发表日期：2014

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BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1

BCAT1 通过氨基酸分解代谢促进携带野生型 IDH1 的神经胶质瘤细胞增殖

期刊:Nature Medicine

影响因子:58.7

doi:10.1038/nm.3217

Martje Tönjes #, Sebastian Barbus #, Yoon Jung Park, Wei Wang, Magdalena Schlotter, Anders M Lindroth, Sabrina V Pleier, Alfa H C Bai, Daniela Karra, Rosario M Piro, Jörg Felsberg, Adele Addington, Dieter Lemke, Irene Weibrecht, Volker Hovestadt, Claudio G Rolli, Benito Campos, Sevin Turcan, Dominik

发表日期：2013

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An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells

突变IDH1的抑制剂可延缓胶质瘤细胞的生长并促进其分化

影响因子:44.7

doi:10.1126/science.1236062

Dan Rohle, Janeta Popovici-Muller, Nicolaos Palaskas, Sevin Turcan, Christian Grommes, Carl Campos, Jennifer Tsoi, Owen Clark, Barbara Oldrini, Evangelia Komisopoulou, Kaiko Kunii, Alicia Pedraza, Stefanie Schalm, Lee Silverman, Alexandra Miller, Fang Wang, Hua Yang, Yue Chen, Andrew Kernytsky, Marc

发表日期：2013

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Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine

DNMT 抑制剂地西他滨可有效诱导 IDH1 突变型胶质瘤细胞分化并抑制其生长

期刊:Oncotarget

doi:10.18632/oncotarget.1412

Sevin Turcan, Armida W M Fabius, Alexandra Borodovsky, Alicia Pedraza, Cameron Brennan, Jason Huse, Agnes Viale, Gregory J Riggins, Timothy A Chan

细胞生物学

发表日期：2013

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IDH mutation impairs histone demethylation and results in a block to cell differentiation

IDH 突变会损害组蛋白去甲基化并导致细胞分化受阻

影响因子:50.5

doi:10.1038/nature10860

Chao Lu, Patrick S Ward, Gurpreet S Kapoor, Dan Rohle, Sevin Turcan, Omar Abdel-Wahab, Christopher R Edwards, Raya Khanin, Maria E Figueroa, Ari Melnick, Kathryn E Wellen, Donald M O'Rourke, Shelley L Berger, Timothy A Chan, Ross L Levine, Ingo K Mellinghoff, Craig B Thompson

细胞生物学

发表日期：2012

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IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

IDH1 突变足以建立胶质瘤高甲基化表型

影响因子:50.5

doi:10.1038/nature10866

Sevin Turcan, Daniel Rohle, Anuj Goenka, Logan A Walsh, Fang Fang, Emrullah Yilmaz, Carl Campos, Armida W M Fabius, Chao Lu, Patrick S Ward, Craig B Thompson, Andrew Kaufman, Olga Guryanova, Ross Levine, Adriana Heguy, Agnes Viale, Luc G T Morris, Jason T Huse, Ingo K Mellinghoff, Timothy A Chan

发表日期：2012

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Corticotropin-releasing factor-2 activation prevents gentamicin-induced oxidative stress in cells derived from the inner ear

促皮质素释放因子-2的激活可防止庆大霉素诱导的内耳细胞氧化应激

期刊:Journal of Neuroscience Research

影响因子:2.9

doi:10.1002/jnr.22449

Johnvesly Basappa, Sevin Turcan, Douglas E Vetter

细胞生物学

发表日期：2010

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Multiplexed isobaric tagging protocols for quantitative mass spectrometry approaches to auditory research

用于听觉研究的定量质谱方法的多重同位素标记协议

期刊:Methods in Molecular Biology

doi:10.1007/978-1-59745-523-7_21

Douglas E Vetter, Johnvesly Basappa, Sevin Turcan

发表日期：2009

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