日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intrinsic resistance to RAS inhibitors is driven by dysregulation of KRAS degradation.

RAS抑制剂的内在耐药性是由KRAS降解失调驱动的。

Ivanisevic Tonci, Ma Yan, Van Boxel Emiel, Magits Wout, Lechat Benoit, Koçberber Zeynep, Willnow Phillipp, Fendt Sarah-Maria, Velde Greetje Vande, Sewduth Raj, Sablina Anna A

Molecular Design of Novel Protein-Degrading Therapeutics Agents Currently in Clinical Trial

目前处于临床试验阶段的新型蛋白质降解治疗药物的分子设计

Kacin, Ela; Sewduth, Raj Nayan

Cardiotoxicity of Chemotherapy: A Multi-OMIC Perspective

化疗的心脏毒性:多组学视角

Ma, Yan; Grootaert, Mandy O J; Sewduth, Raj N

K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins

K128泛素化通过扩大与GAP蛋白的结合界面来限制RAS活性

Wout Magits #, Mikhail Steklov #, Hyunbum Jang, Raj N Sewduth, Amir Florentin, Benoit Lechat, Aidana Sheryazdanova, Mingzhen Zhang, Michal Simicek, Gali Prag, Ruth Nussinov, Anna Sablina

Recent Advances in Peptide Drug Discovery: Novel Strategies and Targeted Protein Degradation

肽类药物发现的最新进展:新型策略和靶向蛋白质降解

Vrbnjak, Katarina; Sewduth, Raj Nayan

Relevance of Carcinogen-Induced Preclinical Cancer Models

致癌物诱导的临床前癌症模型的相关性

Sewduth, Raj N; Georgelou, Konstantina

Multi-Omic Approaches in Cancer-Related Micropeptide Identification

癌症相关微肽鉴定中的多组学方法

Vrbnjak, Katarina; Sewduth, Raj Nayan

Targeted STAT1 therapy for LZTR1-driven peripheral nerve sheath tumor

针对LZTR1驱动的周围神经鞘瘤的STAT1靶向治疗

Ivanisevic, Tonci; Steklov, Mikhail; Lechat, Benoit; Cawthorne, Christopher; Gsell, Willy; Velde, Greetje Vande; Deroose, Christophe; Van Laere, Koen; Himmelreich, Uwe; Sewduth, Raj N; Sablina, Anna A

Spatial Mechano-Signaling Regulation of GTPases through Non-Degradative Ubiquitination

通过非降解性泛素化调控GTP酶的空间机械信号传导

Sewduth, Raj N; Carai, Paolo; Ivanisevic, Tonci; Zhang, Mingzhen; Jang, Hyunbum; Lechat, Benoit; Van Haver, Delphi; Impens, Francis; Nussinov, Ruth; Jones, Elizabeth; Sablina, Anna

Novel Therapeutic Approaches Targeting Post-Translational Modifications in Lung Cancer

针对肺癌翻译后修饰的新型治疗方法

Baietti, Maria Francesca; Sewduth, Raj Nayan