日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tobacco Alkaloid Assessment in a DSS-Induced Colitis Mouse Model with a Fully Humanized Immune System

烟草生物碱在具有完全人源化免疫系统的 DSS 诱发结肠炎小鼠模型中的评估

Catherine Verhaeghe, Marja Talikka, Alain Sewer, Nicolas Sierro, Mehdi Auberson, Dariusz Peric, David Bornand, Remi Dulize, Emmanuel Guedj, Patrick Nef, Sebastien P Tabruyn, Julia Hoeng, Manuel C Peitsch, Giuseppe Lo Sasso

Anatabine ameliorates intestinal inflammation and reduces the production of pro-inflammatory factors in a dextran sulfate sodium mouse model of colitis

阿那他宾可减轻葡聚糖硫酸钠诱导的小鼠结肠炎模型中的肠道炎症并减少促炎因子的产生。

Ruiz Castro, Pedro A; Kogel, Ulrike; Lo Sasso, Giuseppe; Phillips, Blaine W; Sewer, Alain; Titz, Bjorn; Garcia, Llenalia; Kondylis, Athanasios; Guedj, Emmanuel; Peric, Dariusz; Bornand, David; Dulize, Remi; Merg, Celine; Corciulo, Maica; Ivanov, Nikolai V; Peitsch, Manuel C; Hoeng, Julia

Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke

一项利用多组学系统毒理学方法研究小鼠肺部,评估两种加热不燃烧烟草制品和香烟烟雾气溶胶的影响。

Titz, Bjoern; Szostak, Justyna; Sewer, Alain; Phillips, Blaine; Nury, Catherine; Schneider, Thomas; Dijon, Sophie; Lavrynenko, Oksana; Elamin, Ashraf; Guedj, Emmanuel; Tsin Wong, Ee; Lebrun, Stefan; Vuillaume, Grégory; Kondylis, Athanasios; Gubian, Sylvain; Cano, Stephane; Leroy, Patrice; Keppler, Brian; Ivanov, Nikolai V; Vanscheeuwijck, Patrick; Martin, Florian; Peitsch, Manuel C; Hoeng, Julia

The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts

暴露于香烟烟雾的小鼠DSS诱导结肠炎严重程度的降低与免疫调节和微生物群落变化有关。

Lo Sasso, Giuseppe; Phillips, Blaine W; Sewer, Alain; Battey, James N D; Kondylis, Athanasios; Talikka, Marja; Titz, Bjoern; Guedj, Emmanuel; Peric, Dariusz; Bornand, David; Dulize, Remi; Merg, Celine; Corciulo, Maica; Ouadi, Sonia; Yanuar, Rendy; Tung, Ching Keong; Ivanov, Nikolai V; Peitsch, Manuel C; Hoeng, Julia

Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice

在为期 18 个月的 A/J 小鼠系统毒理学研究中,暴露于候选改良风险烟草产品 THS 2.2 的气溶胶对呼吸系统的影响

Bjoern Titz, Alain Sewer, Karsta Luettich, Ee Tsin Wong, Emmanuel Guedj, Catherine Nury, Thomas Schneider, Yang Xiang, Keyur Trivedi, Grégory Vuillaume, Patrice Leroy, Ansgar Büttner, Florian Martin, Nikolai V Ivanov, Patrick Vanscheeuwijck, Julia Hoeng, Manuel C Peitsch

A meta-analysis of microRNAs expressed in human aerodigestive epithelial cultures and their role as potential biomarkers of exposure response to nicotine-containing products

一项关于人类呼吸消化道上皮细胞培养物中表达的microRNA及其作为尼古丁产品暴露反应潜在生物标志物的荟萃分析

Sewer, Alain; Zanetti, Filippo; Iskandar, Anita R; Guedj, Emmanuel; Dulize, Remi; Peric, Dariusz; Bornand, David; Mathis, Carole; Martin, Florian; Ivanov, Nikolai V; Peitsch, Manuel C; Hoeng, Julia

Construction of a Suite of Computable Biological Network Models Focused on Mucociliary Clearance in the Respiratory Tract

构建一套以呼吸道黏液纤毛清除为重点的可计算生物网络模型

Yepiskoposyan, Hasmik; Talikka, Marja; Vavassori, Stefano; Martin, Florian; Sewer, Alain; Gubian, Sylvain; Luettich, Karsta; Peitsch, Manuel Claude; Hoeng, Julia

Systems toxicology meta-analysis of in vitro assessment studies: biological impact of a candidate modified-risk tobacco product aerosol compared with cigarette smoke on human organotypic cultures of the aerodigestive tract

体外评估研究的系统毒理学荟萃分析:候选改良风险烟草产品气溶胶与香烟烟雾对人类呼吸消化道器官培养物的生物学影响比较

Iskandar, A R; Titz, B; Sewer, A; Leroy, P; Schneider, T; Zanetti, F; Mathis, C; Elamin, A; Frentzel, S; Schlage, W K; Martin, F; Ivanov, N V; Peitsch, M C; Hoeng, J

Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach

候选改良风险烟草产品气溶胶和香烟烟雾对人类类器官小气道培养物的比较效应:系统毒理学方法

Iskandar, Anita R; Martinez, Yannick; Martin, Florian; Schlage, Walter K; Leroy, Patrice; Sewer, Alain; Torres, Laura Ortega; Majeed, Shoaib; Merg, Celine; Trivedi, Keyur; Guedj, Emmanuel; Frentzel, Stefan; Mathis, Carole; Ivanov, Nikolai V; Peitsch, Manuel C; Hoeng, Julia

Mechanistic Evaluation of the Impact of Smoking and Chronic Obstructive Pulmonary Disease on the Nasal Epithelium

吸烟和慢性阻塞性肺病对鼻黏膜上皮影响的机制评估

Marja Talikka, Florian Martin, Alain Sewer, Grégory Vuillaume, Patrice Leroy, Karsta Luettich, Nveed Chaudhary, Michael J Peck, Manuel C Peitsch, Julia Hoeng